OGFOD1 and RPS23

Data Source:
BioGRID (two hybrid)

		OGFOD1	RPS23
Description		2-oxoglutarate and iron dependent oxygenase domain containing 1	ribosomal protein S23
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Cytoplasmic Stress Granule	Nucleoplasm Endoplasmic Reticulum Rough Endoplasmic Reticulum Cytosol Ribosome Membrane Cytosolic Small Ribosomal Subunit Polysomal Ribosome
	Molecular Function	Iron Ion Binding Protein Binding L-ascorbic Acid Binding Peptidyl-proline Dioxygenase Activity Peptidyl-proline 3-dioxygenase Activity	RNA Binding Structural Constituent Of Ribosome Protein Binding
	Biological Process	Regulation Of Translational Termination Cell Population Proliferation Protein Hydroxylation Peptidyl-proline Hydroxylation Stress Granule Assembly	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cytoplasmic Translation Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription Stress Granule Assembly Maintenance Of Translational Fidelity
Pathways			L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs		Ascorbic acid
Diseases
GWAS			Carotid intima media thickness (mean) ( 31801372)
Interacting Genes		3 interacting genes: FEM1A LIG4 RPS23	4 interacting genes: DARS1-AS1 MDM2 OGFOD1 PTEN
Entrez ID		55239	6228
HPRD ID		08553	04729
Ensembl ID		ENSG00000087263	ENSG00000186468
Uniprot IDs		Q8N543	A8K517 P62266
PDB IDs		4NHX 4NHY	4CXG 4CXH 4UG0 4V6X 5A2Q 5AJ0 5FLX 5LKS 5OA3 5T2C 5VYC 6EK0 6FEC 6G18 6G4S 6G4W 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6XA1 6Y0G 6Y2L 6Y57 6YBW 6Z6L 6Z6M 6Z6N 6ZLW 6ZM7 6ZME 6ZMI 6ZMO 6ZMT 6ZMW 6ZN5 6ZOJ 6ZOK 6ZON 6ZP4 6ZVH 6ZVJ 7A09 7K5I
Enriched GO Terms of Interacting Partners?
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