MACO1 and LCE2C

Data Source:
BioGRID (two hybrid)

		MACO1	LCE2C
Description		macoilin 1	late cornified envelope 2C
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Integral Component Of Membrane Axon Rough Endoplasmic Reticulum Membrane Nuclear Membrane Neuron Projection Terminus Synapse
	Molecular Function	Molecular_function Protein Binding Microtubule Binding Actin Filament Binding	Protein Binding Identical Protein Binding
	Biological Process	Chemotaxis Brain Development Neuronal Signal Transduction	Keratinization
Pathways			Formation of the cornified envelope
Drugs
Diseases
GWAS		LDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011)
Interacting Genes		23 interacting genes: CRCT1 HOXA1 KRTAP5-2 KRTAP5-7 LCE1C LCE1D LCE1E LCE1F LCE2C LCE3A LCE3E LINGO1 MEI4 MEOX2 NBPF19 NOTCH2NLA NR4A3 POTEB3 SMAD9 SMCP SRPK2 TMEM190 ZNF655	84 interacting genes: ADAMTSL4 ALPP C1orf94 CATSPER1 CCDC125 CHIC2 CRCT1 CREB5 CYP21A2 CYSRT1 EFEMP1 EFEMP2 EFNA3 FAM221B HOXA1 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-10 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP12-3 KRTAP12-4 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2D LCE3A LCE3B LCE3D LCE4A LCE5A MACO1 NBPF19 NECTIN2 NOTCH2NLA NTAQ1 NUFIP2 OTX1 PCSK5 PIAS2 PTPMT1 RGS17 RGS20 RNF4 SLC39A7 SMCP SPRY1 TAP1 TGFB1 TM7SF2 TRIM42 UBE2I VASN VWC2 XAGE3
Entrez ID		55219	353140
HPRD ID		13340	13972
Ensembl ID		ENSG00000204178	ENSG00000187180
Uniprot IDs		Q8N5G2	Q5TA81
PDB IDs
Enriched GO Terms of Interacting Partners?
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