PLEKHG6 and CEP55

Data Source:
BioGRID (two hybrid)

		PLEKHG6	CEP55
Description		pleckstrin homology and RhoGEF domain containing G6	centrosomal protein 55
Image		No pdb structure
GO Annotations	Cellular Component	Spindle Pole Cytoplasm Centrosome Microvillus Cell Junction Cleavage Furrow	Cytoplasm Centrosome Centriole Plasma Membrane Membrane Midbody Cleavage Furrow Centriolar Satellite Intercellular Bridge Flemming Body
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity GTPase Activator Activity Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Positive Regulation Of GTPase Activity	Mitotic Cytokinesis Nucleus Organization Mitotic Metaphase Plate Congression Multicellular Organism Development Regulation Of Phosphatidylinositol 3-kinase Signaling Establishment Of Protein Localization Midbody Abscission Cranial Skeletal System Development
Pathways
Drugs
Diseases
GWAS		Alopecia areata ( 25608926) Colorectal cancer ( 24836286) Colorectal cancer or advanced adenoma ( 30510241) Obesity-related traits ( 23251661) Primary biliary cholangitis ( 26394269)	High density lipoprotein cholesterol levels ( 30498476) Metabolite levels ( 23823483)
Interacting Genes		3 interacting genes: CEP55 RAC1 RHOA	77 interacting genes: AKAP9 ANXA11 ARHGEF15 C1orf109 C1orf216 CBY2 CCBE1 CCDC120 CCHCR1 CDC37 CDC45 CDK1 CDSN CEP57L1 COL8A1 DTNB ECSIT EIF1AD ENKD1 FAM161B FAM90A1 FBF1 FXR2 GOLGA2 GOLGA8DP HAUS1 HGS HSF2BP KANK2 KIFC3 LGALS4 LRRC23 MAPK1 MAPK1IP1L MFAP1 MIA3 MORF4L2 NDEL1 NOS3 NTAQ1 PCNT PDCD6IP PEF1 PIN1 PLEKHG6 PLK1 POLM POM121 PPP1R16B PSEN2 PSMC2 PTPN23 PWWP3A RAB3D RBM14 RBM17 RBM22 RCOR3 RNF32 SDCBP SNRPB SNW1 SS18L1 SUPT5H TCL1A TEAD4 TEX11 TEX14 TFG TP53BP2 TSG101 UBC VPS37C VPS37D WASHC1 WASHC3 ZNF48
Entrez ID		55200	55165
HPRD ID		07692	12569
Ensembl ID		ENSG00000008323	ENSG00000138180
Uniprot IDs		A0A2X0TW08 Q3KR16	Q53EZ4
PDB IDs			3E1R 3WUT 3WUU 3WUV
Enriched GO Terms of Interacting Partners?
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