RESF1 and TBC1D4

Data Source:
HPRD (two hybrid)

		RESF1	TBC1D4
Description		retroelement silencing factor 1	TBC1 domain family member 4
Image		No pdb structure
GO Annotations	Cellular Component	Gamma-tubulin Complex Nucleus	Cytosol Vesicle
	Molecular Function	Protein Binding Histone Binding	GTPase Activator Activity Protein Binding
	Biological Process	Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Positive Regulation Of DNA Methylation-dependent Heterochromatin Assembly	Intracellular Protein Transport Vesicle-mediated Transport Negative Regulation Of Vesicle Fusion Cellular Response To Insulin Stimulus Activation Of GTPase Activity
Pathways			Translocation of SLC2A4 (GLUT4) to the plasma membrane
Drugs
Diseases
GWAS			Diabetic retinopathy ( 23562823) Eosinophil counts ( 32888494) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Heart failure ( 20445134) Mean corpuscular hemoglobin ( 29403010 32888494) Mean corpuscular volume ( 29403010 32888494 27863252) Mean platelet volume ( 27863252) Mean reticulocyte volume ( 32888494) Red blood cell count ( 29403010 32888494 27863252) Two-hour glucose ( 25043022) Type 2 diabetes ( 29926116) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		5 interacting genes: EXOC1 KRT36 KRT86 MDM2 TBC1D4	16 interacting genes: AKT1 CDK5RAP2 EP400 FBXW11 LAMTOR5 NAV1 NFAT5 PIN1 RBM12 RESF1 TASOR TET2 TOPBP1 U2SURP YWHAG ZMIZ1
Entrez ID		55196	9882
HPRD ID		07691	18164
Ensembl ID		ENSG00000174718	ENSG00000136111
Uniprot IDs		Q9HCM1	A0A3B3IRT3 O60343
PDB IDs			3QYB
Enriched GO Terms of Interacting Partners?
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