PBRM1 and PCBP4

Data Source:
BioGRID (affinity chromatography technology)

		PBRM1	PCBP4
Description		polybromo 1	poly(rC) binding protein 4
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromosome Nucleoplasm RSC-type Complex	Nucleus Cytoplasm Cytosol
	Molecular Function	DNA Binding Chromatin Binding Protein Binding	DNA Binding RNA Binding MRNA Binding MRNA 3'-UTR Binding
	Biological Process	Mitotic Cell Cycle Chromatin Remodeling Negative Regulation Of Cell Population Proliferation ATP-dependent Chromatin Remodeling	DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Regulation Of Gene Expression Regulation Of MRNA Stability Negative Regulation Of MRNA Splicing, Via Spliceosome Regulation Of RNA Metabolic Process
Pathways		RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known	TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest Transcriptional activation of cell cycle inhibitor p21 FOXO-mediated transcription of cell cycle genes
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972 31043756) Bipolar disorder with mood-incongruent psychosis ( 23092984) Blood protein levels ( 29875488) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) General cognitive ability ( 29844566) Hemoglobin levels ( 32327693) Insomnia symptoms (never/rarely vs. sometimes/usually) ( 30804566) Intelligence (MTAG) ( 29326435) Lymphocyte counts ( 32888494) Major mood disorders ( 20081856) Monocyte count ( 32888494) Red cell distribution width ( 32888494) Schizophrenia ( 28991256 25056061 29483656 30285260 23974872) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for body mass index ( 28448500) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500)
Interacting Genes		11 interacting genes: APP H2AC20 H2BC21 H3C1 H4C1 PTEN PTS SMARCA4 SUMO2 ZDHHC17 ZNF512B	5 interacting genes: LYST PCBP1 QKI RBFOX1 RNF138
Entrez ID		55193	57060
HPRD ID		07302	16343
Ensembl ID		ENSG00000163939	ENSG00000090097
Uniprot IDs		Q86U86	A0A024R2Y0 C9J0A4 P57723
PDB IDs		2KTB 3G0J 3HMF 3IU5 3IU6 3K2J 3LJW 3MB4 3TLP 4Q0N 4Q0O 4Y03 5E7D 5FH6 5FH7 5FH8 5HRV 5HRW 5HRX 5II1 5II2 5IID 6OXB 6ZN6 6ZNV 6ZS3 6ZS4
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?