SAMD4B and LRRC8E

Data Source:
BioGRID (two hybrid)

		SAMD4B	LRRC8E
Description		sterile alpha motif domain containing 4B	leucine rich repeat containing 8 VRAC subunit E
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	P-body Nucleus Cytosol	Cytoplasm Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Plasma Membrane Ion Channel Complex
	Molecular Function	RNA Binding MRNA Binding Protein Binding Translation Repressor Activity	Volume-sensitive Anion Channel Activity Protein Binding
	Biological Process	Nuclear-transcribed MRNA Poly(A) Tail Shortening Negative Regulation Of Translation Regulation Of MRNA Stability	Inorganic Anion Transport Aspartate Transmembrane Transport Transmembrane Transport Cellular Response To Osmotic Stress Anion Transmembrane Transport
Pathways			Miscellaneous transport and binding events
Drugs
Diseases			Agammaglobulinemias, including the following six diseases: X-linked agammaglobulinemia (Bruton's agammaglobulinemia, XLA); IgM heavy chain gene deletions; Ig-alpha defect; Autosomal recessive agammaglobulinaemia; B cell-linker protein (BLNK) deficiency; Leucine-rich repeat-containing 8
GWAS		Obesity-related traits ( 23251661)
Interacting Genes		7 interacting genes: BCL2L10 CCDC179 LRRC8E NUTM1 RSRC2 USP53 YWHAG	7 interacting genes: FBXO7 GPSM2 LNX2 NUTM1 SAMD4B TRIM2 TRIM3
Entrez ID		55095	80131
HPRD ID		10960	08670
Ensembl ID		ENSG00000179134	ENSG00000171017
Uniprot IDs		A0A024R0N7 M0QZ22 Q5PRF9 Q66K25 Q8IXP7	Q6NSJ5
PDB IDs
Enriched GO Terms of Interacting Partners?
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