IFT57 and ZDHHC17

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		IFT57	ZDHHC17
Description		intraflagellar transport 57	zinc finger DHHC-type palmitoyltransferase 17
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Centrosome Cilium Axoneme Intraciliary Transport Particle B Photoreceptor Connecting Cilium Ciliary Basal Body Dendrite Terminus Ciliary Tip	Golgi Membrane Golgi Apparatus Integral Component Of Membrane Aggresome Cytoplasmic Vesicle Membrane Golgi-associated Vesicle Membrane Presynaptic Membrane Cell Projection Intracellular Membrane-bounded Organelle
	Molecular Function	DNA Binding Protein Binding	Signaling Receptor Binding Protein Binding Magnesium Ion Transmembrane Transporter Activity Palmitoyltransferase Activity Protein-cysteine S-palmitoyltransferase Activity Identical Protein Binding
	Biological Process	Neural Tube Closure Heart Looping Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Smoothened Signaling Pathway Intraciliary Transport Involved In Cilium Assembly Intraciliary Transport Regulation Of Apoptotic Process Motile Cilium Assembly Negative Regulation Of Epithelial Cell Proliferation Left/right Pattern Formation Non-motile Cilium Assembly	Axonogenesis Protein Phosphopantetheinylation Peptidyl-L-cysteine S-palmitoylation Protein Palmitoylation Lipoprotein Transport Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Neurotrophin TRK Receptor Signaling Pathway Regulation Of ERK1 And ERK2 Cascade Magnesium Ion Transmembrane Transport
Pathways		Hedgehog 'off' state Intraflagellar transport Intraflagellar transport
Drugs
Diseases
GWAS		Adult body size ( 32376654) Bipolar disorder ( 31043756) Regular attendance at a religious group ( 29970889)	Mean arterial pressure x educational attainment (some college) interaction (2df) ( 32372009) Metabolite levels ( 23823483) Visceral fat ( 30942860)
Interacting Genes		8 interacting genes: EXOC5 HIP1 IFT20 SKA2 UBXN10 WASHC1 YAF2 ZDHHC17	192 interacting genes: - ABCG4 ACTR1B ADD1 AHDC1 AIDA AK3 ALKBH3 ANKRD50 ANXA11 APBB1IP ARFGAP3 ASF1A ASIC4 BCAS3 BEX2 BTF3 C1orf216 C20orf141 CBS CCDC120 CCDC7 CCNE2 CDSN CENPBD1P1 CHMP1A CIB1 CLRN3 CNDP2 CNKSR1 COG3 CSTA CTCFL CTHRC1 DALRD3 DELE1 DIXDC1 DLG4 DLK1 DR1 DTX3 E2F8 EDRF1 EEF1G ERCC6L EVL EXOSC9 EYA3 FAM207A FAM9A FBH1 FOXD4L6 FTL FUT2 FUT9 GABPB1 GABPB2 GATA1 GOLPH3L GPR135 GRB10 GUSBP3 H2AP H2BC9 H3C10 HBG1 HECTD3 HLA-A HLA-DRB1 HMBS HOXA3 HS1BP3 HTT IFT20 IFT57 INPP5D JMJD7-PLA2G4B KHDC4 KIAA0408 KNSTRN KRAS KRT17 KRT8P12 KRTAP11-1 KRTAP9-2 LCA5L LGALS9C LIN28A LMAN2L LNCRI LRRC45 LY6G6C MANF MAP3K19 MIIP MLH3 MRFAP1 MRFAP1L1 MSANTD3 MSRB2 MYBPHL MYOZ2 NCBP1 NEBL NFATC2IP NFYC NIFK NPFF ODF2 OFCC1 OTUD7B OTX2 PABIR3 PBRM1 PDZK1IP1 PHF5A PLEKHB1 PPP1R21 PPTC7 PRMT5 PTMA QRICH1 RAB39B RAD51 RANGRF RAP1B RBM5 RCAN3 RIC8A RNF20 RNF38 RSBN1L RUBCNL SCNM1 SEMA4G SF3A3 SHOX2 SKA3 SLC1A3 SLC25A31 SLC9A9 SMARCB1 SNAP25 SOX14 SP2 SPRED2 SPRY3 SPRY4 SREBF2 SRSF4 STK25 STN1 SUMF2 SYT1 TEAD1 THAP7 TIGD1 TMC6 TMCC1 TMEM115 TMEM186 TMTC1 TNFAIP1 TNFSF10 TOX TPGS2 TTC23 TTLL7 TUT7 TXNDC12 TXNDC15 UBAC1 UBE2K USP18 USP32 VN1R10P VSX2 WAC WDR20 YIF1A YTHDF3 ZCCHC17 ZFC3H1 ZFP2 ZFP36 ZFYVE19 ZNF333 ZNF341 ZNF597 ZNF624 ZNF667-AS1 ZSCAN9
Entrez ID		55081	23390
HPRD ID		09430	09697
Ensembl ID		ENSG00000114446	ENSG00000186908
Uniprot IDs		Q9NWB7	Q8IUH5
PDB IDs			3EU9 5W7I 5W7J
Enriched GO Terms of Interacting Partners?
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