ZWILCH and ZW10

Data Source:
HPRD (in vivo, in vitro)

		ZWILCH	ZW10
Description		zwilch kinetochore protein	zw10 kinetochore protein
Image			No pdb structure
GO Annotations	Cellular Component	Kinetochore Condensed Chromosome Kinetochore Cytosol RZZ Complex	Kinetochore Condensed Chromosome Kinetochore Spindle Pole Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Kinetochore Microtubule Cytosol Membrane Dsl1/NZR Complex RZZ Complex
	Molecular Function	Protein Binding	Protein Binding Centromeric DNA Binding
	Biological Process	Protein Localization To Kinetochore Cell Division Signal Transduction Involved In Mitotic Cell Cycle Checkpoint	Mitotic Sister Chromatid Segregation Establishment Of Mitotic Spindle Orientation Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Golgi Organization Mitotic Metaphase Plate Congression Mitotic Spindle Assembly Checkpoint Regulation Of Exit From Mitosis Protein Transport Protein Localization To Kinetochore Cell Division Meiotic Cell Cycle Protein-containing Complex Assembly Signal Transduction Involved In Mitotic Cell Cycle Checkpoint
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins COPI-dependent Golgi-to-ER retrograde traffic Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Body mass index ( 29273807)	Parental longevity (father's attained age) ( 29227965)
Interacting Genes		2 interacting genes: KNTC1 ZW10	7 interacting genes: APP DCTN2 PIAS4 PTF1A RINT1 ZWILCH ZWINT
Entrez ID		55055	9183
HPRD ID		07640	04902
Ensembl ID		ENSG00000174442	ENSG00000086827
Uniprot IDs		A8K4T3 Q9H900	O43264
PDB IDs		3IF8
Enriched GO Terms of Interacting Partners?
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