TXNL4B and PRPF6

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		TXNL4B	PRPF6
Description		thioredoxin like 4B	pre-mRNA processing factor 6
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GO Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex U5 SnRNP Cytosol U4/U6 X U5 Tri-snRNP Complex	Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP Membrane Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	Protein Binding	Transcription Coactivator Activity RNA Binding Protein Binding Ribonucleoprotein Complex Binding Androgen Receptor Binding
	Biological Process	MRNA Splicing, Via Spliceosome Cell Cycle	Spliceosomal Tri-snRNP Complex Assembly Spliceosomal Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Localization RNA Splicing Positive Regulation Of Transcription By RNA Polymerase II
Pathways			mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Blood protein levels ( 29875488 28240269) Coronary artery disease ( 29212778) Hematocrit ( 32888494) Hemoglobin ( 32888494) LDL cholesterol levels ( 32203549) Low density lipoprotein cholesterol levels ( 30718733 32154731) Medication use (HMG CoA reductase inhibitors) ( 31015401) Red blood cell count ( 32888494) Total cholesterol levels ( 30718733) Triglyceride levels ( 32203549 32154731)	Body mass index ( 28552196) Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Prostate cancer ( 23535732) Refractive error ( 32231278)
Interacting Genes		14 interacting genes: AIPL1 ALKBH4 BHLHE40 CENATAC MEOX1 MEOX2 PICK1 PLEKHF2 PNMA5 PRPF6 REL SF1 SPG21 TCF4	12 interacting genes: AR ARAF CD2BP2 ESR1 NR3C1 RAF1 SMARCA2 SRRM2 SUMO2 TIMM44 TXNL4B YWHAB
Entrez ID		54957	24148
HPRD ID		11655	10729
Ensembl ID		ENSG00000140830	ENSG00000101161
Uniprot IDs		Q9NX01	O94906
PDB IDs		1XBS 3GIX 4IN0	3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
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