POU6F1 and ACOT7

Data Source:
BioGRID (two hybrid)

		POU6F1	ACOT7
Description		POU class 6 homeobox 1	acyl-CoA thioesterase 7
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GO Annotations	Cellular Component	Chromatin Nucleus	Nucleoplasm Mitochondrion Cytosol Extracellular Exosome
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding	Fatty-acyl-CoA Binding Protein Binding Palmitoyl-CoA Hydrolase Activity Long-chain Fatty Acyl-CoA Binding Protein Homodimerization Activity Acyl-CoA Hydrolase Activity Carboxylic Ester Hydrolase Activity Myristoyl-CoA Hydrolase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Brain Development Heart Development Muscle Organ Development	Fatty Acid Metabolic Process Acyl-CoA Metabolic Process Coenzyme A Biosynthetic Process Medium-chain Fatty-acyl-CoA Catabolic Process Long-chain Fatty-acyl-CoA Catabolic Process Medium-chain Fatty Acid Biosynthetic Process Palmitic Acid Biosynthetic Process
Pathways			Mitochondrial Fatty Acid Beta-Oxidation
Drugs
Diseases
GWAS		Adult body size ( 32376654) Cisplatin-induced ototoxicity ( 28039263) Mean corpuscular hemoglobin ( 32888494)	Asthma exacerbations in inhaled corticosteroid treatment ( 30697902) Metabolite levels ( 31628463) QT interval ( 19305408)
Interacting Genes		3 interacting genes: ACOT7 ERBB2 NFYC	24 interacting genes: ACOT12 ATXN1 ATXN1L BAG4 CAMK2B CDC42 CRYAB DAZAP2 DLC1 ENKD1 LMNA MAGEA3 MAGEA6 NCOA5 POT1 POU6F1 SPATC1L TERF1 THAP1 TINF2 UBQLN1 UBQLN2 UBXN1 ZNF438
Entrez ID		5463	11332
HPRD ID		17883	12517
Ensembl ID		ENSG00000184271	ENSG00000097021
Uniprot IDs		A0A1C7CYV8 B3KT91 Q14863	O00154
PDB IDs		3D1N	2QQ2
Enriched GO Terms of Interacting Partners?
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