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DDX49 and MIR15A
Data Source:
BioGRID
(unspecified method)
DDX49
MIR15A
Description
DEAD-box helicase 49
microRNA 15a
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Extracellular Space
Extracellular Exosome
Extracellular Vesicle
Molecular Function
RNA Binding
RNA Helicase Activity
Protein Binding
ATP Binding
MRNA 3'-UTR Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
Biological Process
RRNA Processing
Positive Regulation Of Cell Growth
Regulation Of RRNA Stability
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Negative Regulation Of Cell Population Proliferation
Negative Regulation Of Peptidyl-threonine Phosphorylation
Negative Regulation Of Angiogenesis
Negative Regulation Of NF-kappaB Transcription Factor Activity
Gene Silencing By MiRNA
MiRNA Mediated Inhibition Of Translation
Positive Regulation Of Apoptotic Process
Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Negative Regulation Of Inflammatory Response
Cellular Response To Glucose Stimulus
Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis
Negative Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis
Negative Regulation Of Vascular Endothelial Growth Factor Production
Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Negative Regulation Of Vascular Associated Smooth Muscle Cell Migration
Negative Regulation Of Cell Chemotaxis To Fibroblast Growth Factor
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Positive Regulation Of Endothelial Cell Apoptotic Process
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
rRNA modification in the nucleus and cytosol
Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS
Cerebrospinal fluid p-Tau181p:AB1-42 ratio (
26252872
)
Cerebrospinal P-tau181p levels (
26252872
)
Interacting Genes
11 interacting genes:
APP
HAP1
MIR1-2
MIR138-2
MIR140
MIR15A
MIR199A1
MIR214
PAGE1
PSMB2
STX1A
73 interacting genes:
AIMP1
AIMP2
C1QBP
CPSF1
DARS1
DDX1
DDX21
DDX3X
DDX49
DHX36
DHX37
EIF2AK2
EPRS1
ERAL1
FAM98A
FUS
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
LARP7
LARS1
LIN28A
LIN28B
LRPPRC
MARS1
MATR3
MSI2
MYEF2
NOL6
NONO
NUDT21
PDCD11
PGAM5
PLOD1
PRMT1
PTBP1
PUF60
QARS1
RARS1
RBM14
RTCA
RTCB
SF3A1
SF3B1
SF3B2
SF3B3
SFPQ
SPOUT1
SYNCRIP
TAF15
TRA2A
TRA2B
TRIM71
TRMT10C
UPF1
UTP20
YBX1
YBX3
ZNF346
Entrez ID
54555
406948
HPRD ID
10864
Ensembl ID
ENSG00000105671
ENSG00000283785
Uniprot IDs
Q9Y6V7
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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