GNL3L and PRKAR1B

Data Source:
BioGRID (two hybrid)

		GNL3L	PRKAR1B
Description		G protein nucleolar 3 like	protein kinase cAMP-dependent type I regulatory subunit beta
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Telomerase Holoenzyme Complex Nucleolus Cytosol Membrane	Multivesicular Body Cytosol Plasma Membrane CAMP-dependent Protein Kinase Complex Ciliary Base Schaffer Collateral - CA1 Synapse Hippocampal Mossy Fiber To CA3 Synapse Glutamatergic Synapse
	Molecular Function	RNA Binding Protein Binding GTP Binding	CAMP-dependent Protein Kinase Inhibitor Activity Protein Binding CAMP-dependent Protein Kinase Regulator Activity CAMP Binding Protein Kinase A Catalytic Subunit Binding
	Biological Process	Positive Regulation Of Protein-containing Complex Assembly Negative Regulation Of Protein Ubiquitination Regulation Of Protein Stability Negative Regulation Of Protein Binding Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Protein Sumoylation Ribosome Biogenesis Positive Regulation Of Protein Localization To Chromosome, Telomeric Region	Renal Water Homeostasis Protein Phosphorylation Blood Coagulation Learning Or Memory Regulation Of Protein Kinase A Signaling Activation Of Protein Kinase A Activity Regulation Of CAMP-mediated Signaling Modulation Of Chemical Synaptic Transmission Cellular Response To Glucagon Stimulus Regulation Of Synaptic Vesicle Cycle Negative Regulation Of CAMP-dependent Protein Kinase Activity
Pathways			PKA activation PKA activation in glucagon signalling DARPP-32 events Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Vasopressin regulates renal water homeostasis via Aquaporins CREB1 phosphorylation through the activation of Adenylate Cyclase Hedgehog 'off' state ADORA2B mediated anti-inflammatory cytokines production FCGR3A-mediated IL10 synthesis Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Prostate cancer ( 31562322)	Body size at age 10 ( 32376654) Hematocrit ( 32888494 27863252) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Plasma free amino acid levels ( 30659259) Red blood cell count ( 32888494 27863252)
Interacting Genes		13 interacting genes: ADRB2 ALAS1 DYNLL1 GOLGA2 HMBOX1 HSF2BP LDOC1 LZTS2 MTUS2 PRKAR1B ROPN1 TERF1 TRIM54	76 interacting genes: AKAP1 AKAP14 AKAP7 ANKS1A BAG3 BAG6 BOD1L2 CAMSAP1 CBX8 CCDC103 CCDC187 CDC37 CDKN1A CEP19 COX5B DACH1 DTNB EEF2KMT EGFR FAM161A FAM90A1 FCHSD2 GAS2L2 GLIS2 GNL3L GOLGA1 GPKOW GUCA1A IGFN1 INPP5J KANK2 KIF5B L3MBTL2 LENG1 LNX1 MBD3 MED8 MYO15B NTAQ1 NXF1 PIK3R3 POLE4 PPP1R9A PRKAA2 PRKACA PRKAR1A PRPF18 PSMG1 QRICH1 RARG RUNX1T1 SAP30BP SH2D4A SHC3 SMAD3 SMAD4 SMG9 SNW1 STK16 SYTL4 TASOR2 TEAD4 THRA TSGA10IP UACA VEZF1 WNK1 WRN ZBTB16 ZMYND19 ZNF177 ZNF329 ZNF35 ZNF410 ZNF559-ZNF177 ZNF76
Entrez ID		54552	5575
HPRD ID		06514	01485
Ensembl ID		ENSG00000130119	ENSG00000188191
Uniprot IDs		A0A024R9Y6 Q05DU1 Q9NVN8	P31321
PDB IDs			4DIN 4F9K
Enriched GO Terms of Interacting Partners?
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