KRT20 and EIF4E2

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KRT20	EIF4E2
Description		keratin 20	eukaryotic translation initiation factor 4E family member 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Intermediate Filament	P-body Cytoplasm Cytosol MRNA Cap Binding Complex Eukaryotic Translation Initiation Factor 4F Complex
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding	RNA Cap Binding RNA 7-methylguanosine Cap Binding RNA Binding Translation Initiation Factor Activity Protein Binding Translation Factor Activity, RNA Binding Ubiquitin Protein Ligase Binding
	Biological Process	Apoptotic Process Cellular Response To Starvation Keratinization Intermediate Filament Organization Regulation Of Protein Secretion Cornification	Translational Initiation Negative Regulation Of Translation Gene Silencing By RNA Positive Regulation Of MiRNA Mediated Inhibition Of Translation
Pathways		Keratinization Formation of the cornified envelope	ISG15 antiviral mechanism
Drugs
Diseases
GWAS		Height ( 19893584)	Height ( 25282103) Non-small cell lung cancer (survival) ( 21079520) Refractive error ( 32231278)
Interacting Genes		46 interacting genes: ABI2 AMOTL2 ANKRD36BP1 BBLN BCAS2 CCDC196 CCDC85B COASY CYSRT1 DES EIF4E2 EXOC8 FXR2 KRT13 KRT15 KRT24 KRT27 KRT3 KRT31 KRT34 KRT40 KRT72 KRT75 KRT76 KRT80 KRTAP1-1 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP6-3 NOTCH2NLA NUP62 PIK3R2 PLEKHA5 PPP1R13B PRC1 PRPH SNAPIN TFIP11 TXLNA USHBP1 VIM WASHC1 ZC2HC1C ZC3H14	45 interacting genes: ADAMTSL4 AMOTL2 APP ARIH1 CARD9 CBY2 CDR2 EIF4EBP1 EIF4EBP3 EIF4ENIF1 FBXO25 GIGYF1 HOMEZ KRT13 KRT19 KRT20 KRT31 KRT40 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP4-12 LZTS2 MAGED1 MAPRE3 MDFI MGAT5B MIPOL1 MYOG NECAB2 NOTCH2NLA PRDM14 REL SPAG5 SPRY2 TADA2A TCF4 TLE5 TMCC2 TRIM27 TRIM54 UBXN11 USHBP1 USP54 ZBTB9
Entrez ID		54474	9470
HPRD ID		12193	05798
Ensembl ID		ENSG00000171431	ENSG00000135930
Uniprot IDs		P35900	B8ZZ50 B8ZZL3 B9A023 O60573 Q53RG0 Q59FE1
PDB IDs			2JGB 2JGC 5NVK 5NVL 5NVM 5NVN 5XLN
Enriched GO Terms of Interacting Partners?
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