SLC38A2 and STX11

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SLC38A2	STX11
Description		solute carrier family 38 member 2	syntaxin 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Brush Border Axon Dendrite Sarcolemma Neuronal Cell Body	Golgi Apparatus Plasma Membrane Synaptic Vesicle Endomembrane System Integral Component Of Membrane SNARE Complex Presynaptic Active Zone Membrane
	Molecular Function	Neutral Amino Acid:sodium Symporter Activity Protein Binding Amino Acid Transmembrane Transporter Activity L-glutamine Transmembrane Transporter Activity L-serine Transmembrane Transporter Activity	SNARE Binding SNAP Receptor Activity Protein Binding
	Biological Process	Amino Acid Transmembrane Transport Sodium Ion Transport Amino Acid Transport Glutamine Transport Female Pregnancy Positive Regulation Of Gene Expression Glutamate Secretion Neutral Amino Acid Transport L-serine Transport Cerebral Cortex Development Glycine Betaine Transport Alanine Transport Positive Regulation Of RNA Splicing Cellular Response To Amino Acid Starvation Cellular Response To Mechanical Stimulus Regulation Of Cellular Response To Stress Transport Across Blood-brain Barrier Cellular Response To Arsenite(3-)	Intracellular Protein Transport Exocytosis Vesicle Fusion Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Vesicle Docking Membrane Fusion
Pathways		Glutamate Neurotransmitter Release Cycle Amino acid transport across the plasma membrane
Drugs		Asparagine
Diseases			Familial hemophagocytic lymphohistiocytosis (FHPL), including the following three diseases: Perforin deficiency; Munc deficiency; STX11 deficiency
GWAS		Blond vs. brown/black hair color ( 30531825) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Uterine fibroids ( 31649266)	Nicotine dependence symptom count ( 25555482) Pre-treatment viral load in HIV-1 infection ( 31219150)
Interacting Genes		4 interacting genes: APP DCDC2 STX11 TMEM237	97 interacting genes: APP AXIN1 AXIN2 BLOC1S6 BYSL C1orf109 CARD9 CCBE1 CCDC120 CCDC125 CCDC184 CCDC196 CCDC33 CCHCR1 CCNK CDCA7L CDR2L CRYBA4 CTBP2 CWF19L2 DISC1 DUSP29 EIF1AD EIF2B5 FAM110A FAM161A FAM161B FAM74A4 FAM90A1 FARS2 GOLGA8EP GOLGA8F HAUS1 HGS HOXA1 IKBKG IKZF3 KAT5 KCTD9 KDM1A KIFC3 KLC3 KRT75 KXD1 LENG1 LONRF1 MAGOHB MBD3L1 MBIP MEOX2 MFAP1 MID2 MIS18A NDC80 NTAQ1 PKN1 PPP1R18 PRKAB2 PRPF18 PRPF31 PSMA3 PSMC3 RAD51D RNF6 RNF8 RNPS1 RUNX1T1 SCNM1 SH2D4A SHC3 SIKE1 SLC38A2 SMARCE1 SNAP23 SNAP25 SNX3 SOGA1 STX1A STX4 SUV39H1 TADA3 TAF6L TBK1 TCEA2 TCF4 TLE5 TNFRSF21 TRIM41 TSGA10IP UBASH3A USHBP1 VAMP2 VPS52 ZCCHC10 ZNF19 ZNF417 ZNF587
Entrez ID		54407	8676
HPRD ID		05535	09231
Ensembl ID		ENSG00000134294	ENSG00000135604
Uniprot IDs		A0A024R0W3 Q8NHT5 Q96QD8	O75558
PDB IDs
Enriched GO Terms of Interacting Partners?
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