Wiki-Pi
About
Search
Browse
People
Updates
Search
ATP7A and PDZD11
Data Source:
HPRD
(two hybrid, in vivo)
ATP7A
PDZD11
Description
ATPase copper transporting alpha
PDZ domain containing 11
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Late Endosome
Endoplasmic Reticulum
Golgi Apparatus
Trans-Golgi Network
Cytosol
Plasma Membrane
Microvillus
Membrane
Integral Component Of Membrane
Basolateral Plasma Membrane
Apical Plasma Membrane
Trans-Golgi Network Transport Vesicle
Secretory Granule
Phagocytic Vesicle Membrane
Cell Leading Edge
Brush Border Membrane
Neuron Projection
Neuronal Cell Body
Perikaryon
Membrane Raft
Perinuclear Region Of Cytoplasm
Extracellular Region
Cytosol
Cell-cell Junction
Adherens Junction
Basolateral Plasma Membrane
Synapse
Pore Complex
Presynapse
Molecular Function
Copper Ion Transmembrane Transporter Activity
Copper Ion Binding
Protein Binding
ATP Binding
Superoxide Dismutase Copper Chaperone Activity
Copper-dependent Protein Binding
P-type Divalent Copper Transporter Activity
Chaperone Binding
Cuprous Ion Binding
Protein Binding
Biological Process
Blood Vessel Development
In Utero Embryonic Development
Liver Development
Blood Vessel Remodeling
Regulation Of Oxidative Phosphorylation
Tryptophan Metabolic Process
Catecholamine Metabolic Process
Copper Ion Transport
Cellular Copper Ion Homeostasis
Mitochondrion Organization
Female Pregnancy
Lactation
Locomotory Behavior
Response To Iron(III) Ion
Response To Manganese Ion
Response To Zinc Ion
Detoxification Of Copper Ion
Regulation Of Gene Expression
Positive Regulation Of Lamellipodium Assembly
Copper Ion Import
Peptidyl-lysine Modification
Removal Of Superoxide Radicals
Antimicrobial Humoral Response
Cerebellar Purkinje Cell Differentiation
Pyramidal Neuron Development
Central Nervous System Neuron Development
Extracellular Matrix Organization
Collagen Fibril Organization
Hair Follicle Morphogenesis
Ion Transmembrane Transport
Negative Regulation Of Iron Ion Transmembrane Transport
Cellular Response To Platelet-derived Growth Factor Stimulus
T-helper Cell Differentiation
Epinephrine Metabolic Process
Norepinephrine Metabolic Process
Dopamine Metabolic Process
Serotonin Metabolic Process
Positive Regulation Of Catalytic Activity
Pigmentation
Skin Development
Positive Regulation Of Cell Size
Elastic Fiber Assembly
Lung Alveolus Development
Neuron Projection Morphogenesis
Positive Regulation Of Epithelial Cell Proliferation
Cartilage Development
Positive Regulation Of Oxidoreductase Activity
Elastin Biosynthetic Process
Copper Ion Export
Cellular Response To Amino Acid Stimulus
Cellular Response To Antibiotic
Cellular Response To Cadmium Ion
Cellular Response To Cobalt Ion
Cellular Response To Copper Ion
Cellular Response To Iron Ion
Cellular Response To Lead Ion
Cellular Response To Hypoxia
Inorganic Cation Transmembrane Transport
Positive Regulation Of Response To Wounding
Positive Regulation Of Vascular Associated Smooth Muscle Cell Migration
Regulation Of Cytochrome-c Oxidase Activity
Biotin Metabolic Process
Neurotransmitter Secretion
Pantothenate Metabolic Process
Antimicrobial Humoral Response
Ion Transmembrane Transport
Maintenance Of Epithelial Cell Apical/basal Polarity
Pore Complex Assembly
Transmembrane Transport
Protein Localization To Basolateral Plasma Membrane
Pathways
Detoxification of Reactive Oxygen Species
Ion influx/efflux at host-pathogen interface
Ion transport by P-type ATPases
Biotin transport and metabolism
Vitamin B5 (pantothenate) metabolism
Transport of vitamins, nucleosides, and related molecules
Ion influx/efflux at host-pathogen interface
Ion transport by P-type ATPases
Drugs
Diseases
Spinal muscular atrophy (SMA), including: SMA type I (SMA1) / Werdning-Hoffman disease; SMA type II (SMA2); SMA type III (SMA3) / Kugeleberg-Welander disease; SMA type IV (SMA4); X-linked SMA 2 (SMAX2); X-linked distal SMA 3 (DSMAX); Distal SMA autosomal recessive type 4 (DSMA4); Congenital distal spinal muscular atrophy (SMAL); SMA proximal adult autosomal dominant (SMAPAD)
Distal hereditary motor neuropathies (dHMN)
Menkes disease (MD); Menkes kinky hair syndrome
Cutis laxa, including: Autosomal dominant cutis laxa (ADCL); Autosomal recessive cutis laxa I (ARCL1); Autosomal recessive cutis laxa II (ARCL2); X-linked recessive cutis laxa (XRCL); Wrinkly skin syndrome
GWAS
Height (
31562340
)
Interacting Genes
3 interacting genes:
ATOX1
CP
PDZD11
5 interacting genes:
ATP2B2
ATP7A
MAGI2
PLEKHA5
SIGMAR1
Entrez ID
538
51248
HPRD ID
02054
06622
Ensembl ID
ENSG00000165240
ENSG00000120509
Uniprot IDs
B4DRW0
Q04656
Q762B6
Q5EBL8
PDB IDs
1AW0
1KVI
1KVJ
1Q8L
1S6O
1S6U
1Y3J
1Y3K
1YJR
1YJT
1YJU
1YJV
2AW0
2G9O
2GA7
2K1R
2KIJ
2KMV
2KMX
3CJK
5T7L
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?