PLRG1 and HNRNPM

Data Source:
BioGRID (pull down)

		PLRG1	HNRNPM
Description		pleiotropic regulator 1	heterogeneous nuclear ribonucleoprotein M
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GO Annotations	Cellular Component	Prp19 Complex Fibrillar Center Nucleus Nucleoplasm DNA Replication Factor A Complex Nuclear Speck Nuclear Membrane U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome Cul4-RING E3 Ubiquitin Ligase Complex	Nucleus Nucleoplasm Spliceosomal Complex Nucleolus Cytoplasm Membrane Nuclear Matrix Paraspeckles Collagen-containing Extracellular Matrix Extracellular Exosome Catalytic Step 2 Spliceosome Post-mRNA Release Spliceosomal Complex Ribonucleoprotein Complex
	Molecular Function	Protein Binding	RNA Binding MRNA Binding Protein Binding Protein Domain Specific Binding
	Biological Process	MRNA Splicing, Via Spliceosome Protein Localization To Nucleus Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle	Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Fibroblast Growth Factor Receptor Signaling Pathway RNA Metabolic Process Regulation Of MRNA Stability Involved In Response To Oxidative Stress
Pathways		mRNA Splicing - Major Pathway	FGFR2 alternative splicing mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA
Drugs
Diseases
GWAS		Fibrinogen ( 21757653) Fibrinogen levels ( 29403010 28107422)	Coronary artery disease ( 29212778)
Interacting Genes		14 interacting genes: APP CDC5L CNN1 HNRNPM MIR106B MIR205 MIR93 MIRLET7A2 MIRLET7E MIRLET7G MIRLET7I MX1 SF3B1 ZSCAN1	106 interacting genes: AKAP9 APC CDC5L CEACAM5 DUX4 ECPAS GMCL2 HGS HNRNPF HNRNPH1 JUN LENG8 LMO1 LMO2 LMO3 LYST MAGEA6 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I PLRG1 PRRC2A RBM4 RBM4B SMARCB1 STAT3 SUMO2 TCERG1 TEKT4 TRAF1 TSGA10 U2AF1 UBC UBE2I WDR77 YWHAG ZNF207
Entrez ID		5356	4670
HPRD ID		16181	01188
Ensembl ID		ENSG00000171566	ENSG00000099783
Uniprot IDs		O43660	P52272 Q59ES8
PDB IDs		4YVD 5MQF 5XJC 5YZG 5Z56 5Z57 5Z58 6FF4 6FF7 6ICZ 6ID0 6ID1 6QDV 6ZYM	2DGV 2DH9 2DO0 2OT8
Enriched GO Terms of Interacting Partners?
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