ATP6V1E1 and MESD

Data Source:
BioGRID (two hybrid)

		ATP6V1E1	MESD
Description		ATPase H+ transporting V1 subunit E1	mesoderm development LRP chaperone
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Endosome Cytosol Microvillus Apical Plasma Membrane Proton-transporting Two-sector ATPase Complex Proton-transporting Two-sector ATPase Complex, Catalytic Domain Extracellular Exosome	Endoplasmic Reticulum Plasma Membrane
	Molecular Function	Protein Binding Proton-exporting ATPase Activity, Phosphorylative Mechanism Hydrolase Activity Proton-transporting ATPase Activity, Rotational Mechanism ATPase Binding	Molecular_function Protein Binding Identical Protein Binding Low-density Lipoprotein Particle Receptor Binding
	Biological Process	Insulin Receptor Signaling Pathway Regulation Of Macroautophagy Transferrin Transport Ion Transmembrane Transport Phagosome Acidification Proton Transmembrane Transport	Ossification Protein Folding Phagocytosis Mesoderm Development Wnt Signaling Pathway Protein Localization To Cell Surface Positive Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering
Pathways		ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs		Tiludronic acid
Diseases
GWAS
Interacting Genes		14 interacting genes: ALDOA ALDOB ALDOC APP ATP6V0E1 ATP6V1G1 ATP6V1G2 ATP6V1H HSPB2 MESD SLC9A3R1 SOS1 TRAF6 XRCC6	75 interacting genes: ABCG8 ABITRAM ACBD7 ADAL AKIRIN2 AKNAD1 AKT1 APP ASH2L ATP6V1E1 ATP6V1E2 BORCS8 BORCS8-MEF2B BRD4 C17orf75 CCDC105 CDR2L CENATAC CENPH CHCHD1 CLP1 CNOT9 COL10A1 COL1A2 COX14 COX5A CUTC CYP4F11 DDX6 ENKD1 FAM13C FAM172A FARS2 FCER1A GEM GOLGA7 GPKOW GTPBP3 H2AB2 H2AB3 HSBP1L1 IGF1 KPNB1 LCE1A LRP5 LY96 MAGEB4 MAP1LC3B MCM9 MELTF MKNK2 MRM1 MTNR1A NRDE2 PMF1 PSMA5 QARS1 RCOR3 RFC3 SIK1B SMARCB1 SNX5 SNX7 TEX12 TEX48 TPM2 TREX2 TRMT2A TTC21A TTC23 TYMP UBQLN1 ZNF493 ZNF827 ZNF844
Entrez ID		529	23184
HPRD ID		00163	12129
Ensembl ID		ENSG00000131100	ENSG00000117899
Uniprot IDs		P36543 Q53Y06	Q14696
PDB IDs
Enriched GO Terms of Interacting Partners?
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