Wiki-Pi
About
Search
Browse
People
Updates
Search
PFN1 and VASP
Data Source:
HPRD
(in vitro)
PFN1
VASP
Description
profilin 1
vasodilator stimulated phosphoprotein
Image
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
Cytoskeleton
Focal Adhesion
Cell Cortex
Membrane
Extracellular Exosome
Blood Microparticle
Cytosol
Plasma Membrane
Bicellular Tight Junction
Focal Adhesion
Actin Cytoskeleton
Lamellipodium Membrane
Filopodium Membrane
Extracellular Exosome
Molecular Function
Adenyl-nucleotide Exchange Factor Activity
Phosphotyrosine Residue Binding
RNA Binding
Actin Binding
Actin Monomer Binding
Protein Binding
Phosphatidylinositol-4,5-bisphosphate Binding
Cadherin Binding
Proline-rich Region Binding
Actin Binding
Protein Binding
Profilin Binding
SH3 Domain Binding
Cadherin Binding
Biological Process
Positive Regulation Of Epithelial Cell Migration
Actin Cytoskeleton Organization
Regulation Of Actin Filament Polymerization
Negative Regulation Of Actin Filament Polymerization
Positive Regulation Of Actin Filament Polymerization
Negative Regulation Of Actin Filament Bundle Assembly
Positive Regulation Of Actin Filament Bundle Assembly
Positive Regulation Of ATPase Activity
Protein Stabilization
Negative Regulation Of Stress Fiber Assembly
Wnt Signaling Pathway, Planar Cell Polarity Pathway
Positive Regulation Of Ruffle Assembly
Neural Tube Closure
Axon Guidance
Actin Polymerization Or Depolymerization
Actin Cytoskeleton Organization
Positive Regulation Of Actin Filament Polymerization
Cell Junction Assembly
Protein Homotetramerization
Pathways
Platelet degranulation
Signaling by ROBO receptors
PCP/CE pathway
RHO GTPases Activate Formins
RHO GTPases Activate Formins
Generation of second messenger molecules
Signaling by ROBO receptors
Signaling by ROBO receptors
Cell-extracellular matrix interactions
Drugs
7-HYDROXY-4-METHYL-3-(2-HYDROXY-ETHYL)COUMARIN
Artenimol
Diseases
GWAS
Mean platelet volume (
32888494
)
Alzheimer's disease or HDL levels (pleiotropy) (
30805717
)
Interacting Genes
33 interacting genes:
ACTA1
ACTB
AFDN
APBB1IP
CMA1
CRMP1
DBN1
DLG5
DNM2
ENAH
ERG28
FMNL1
GPHN
LRIF1
MYPOP
NCK1
PIK3R1
RAD51
RHOQ
SIRPA
SRPK1
STUB1
TLE1
TRAF6
TRIM15
UNC119
VASP
VIPR1
WASF1
WASL
WIPF2
XPO6
YWHAQ
44 interacting genes:
ABI1
ABI2
ABI3
ACTA1
ACTG1
APBB1
APBB1IP
CDC42
CEP43
DMRTB1
DNMBP
ENAH
ERMAP
EVL
FAT1
FRS3
FYB1
GSN
IQGAP1
LPP
NOL3
NR4A1
PFN1
PFN2
PLSCR1
PRKACA
PRKG1
PRPF40A
PSORS1C2
RAD51
RAPH1
SAT1
SCGB2A2
SPTA1
TES
TRIM15
TRIM9
VCL
WAS
WASL
WWP2
XIRP1
XPO6
ZYX
Entrez ID
5216
7408
HPRD ID
01452
03415
Ensembl ID
ENSG00000108518
ENSG00000125753
Uniprot IDs
P07737
A0A024R0V4
P50552
PDB IDs
1AWI
1CF0
1CJF
1FIK
1FIL
1PFL
2PAV
2PBD
3CHW
4X1L
4X1M
4X25
6NAS
6NBE
6NBW
1EGX
1JNG
1USD
1USE
2PAV
2PBD
3CHW
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?