ENPP2 and TOR1A

Data Source:
BioGRID (affinity chromatography technology)

		ENPP2	TOR1A
Description		ectonucleotide pyrophosphatase/phosphodiesterase 2	torsin family 1 member A
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GO Annotations	Cellular Component	Extracellular Space Plasma Membrane	Nuclear Envelope Endoplasmic Reticulum Endoplasmic Reticulum Lumen Cytosol Cytoskeleton Synaptic Vesicle Membrane Secretory Granule Growth Cone Cytoplasmic Vesicle Membrane Nuclear Membrane Extrinsic Component Of Endoplasmic Reticulum Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	Nucleic Acid Binding Phosphodiesterase I Activity Nucleotide Diphosphatase Activity Lysophospholipase Activity Scavenger Receptor Activity Calcium Ion Binding Transcription Factor Binding Zinc Ion Binding Hydrolase Activity Polysaccharide Binding Alkylglycerophosphoethanolamine Phosphodiesterase Activity	Protein Binding ATP Binding Cytoskeletal Protein Binding ATPase Activity Kinesin Binding Identical Protein Binding Unfolded Protein Binding Misfolded Protein Binding
	Biological Process	Endocytosis Chemotaxis Immune Response Phospholipid Catabolic Process Positive Regulation Of Epithelial Cell Migration Sphingolipid Catabolic Process Regulation Of Cell Migration Phosphatidylcholine Catabolic Process Regulation Of Angiogenesis Cell Motility Positive Regulation Of Peptidyl-tyrosine Phosphorylation Nucleic Acid Phosphodiester Bond Hydrolysis Positive Regulation Of Lamellipodium Morphogenesis	Protein Deneddylation Response To Oxidative Stress Organelle Organization Nuclear Envelope Organization Cell Adhesion Neuron Projection Development Protein Localization To Nucleus Wound Healing, Spreading Of Cells Intermediate Filament Cytoskeleton Organization Synaptic Vesicle Transport Chaperone Cofactor-dependent Protein Refolding Regulation Of Dopamine Uptake Involved In Synaptic Transmission Chaperone-mediated Protein Folding ER-associated Misfolded Protein Catabolic Process Nuclear Membrane Organization Chaperone-mediated Protein Transport Positive Regulation Of Synaptic Vesicle Endocytosis Regulation Of Protein Localization To Cell Surface
Pathways		Vitamin B5 (pantothenate) metabolism	Cargo recognition for clathrin-mediated endocytosis
Drugs
Diseases			Primary torsion dystonia (PTD)
GWAS		Appendicular lean mass ( 33097823) Birth weight ( 31043758) Brain morphology (MOSTest) ( 32665545) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Height ( 21998595 28552196 31562340) Offspring birth weight ( 31043758)	Prostate cancer ( 29892016) Prostate cancer (advanced) ( 29892016) Prostate cancer (early onset) ( 29892016)
Interacting Genes		1 interacting genes: HSPB1	7 interacting genes: KRTAP10-7 LMNA LRRC7 MDFI SNCA TOR1AIP2 TOR1B
Entrez ID		5168	1861
HPRD ID		03037	06897
Ensembl ID		ENSG00000136960	ENSG00000136827
Uniprot IDs		E7EUF1 Q13822	B3KPA1 O14656
PDB IDs		4ZG6 4ZG7 4ZG9 4ZGA 5KXA 5M7M 5MHP	5J1S 5J1T 6OIF
Enriched GO Terms of Interacting Partners?
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