TOR1A and TOR1B

Data Source:
HPRD (in vitro)

		TOR1A	TOR1B
Description		torsin family 1 member A	torsin family 1 member B
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Endoplasmic Reticulum Endoplasmic Reticulum Lumen Cytosol Cytoskeleton Synaptic Vesicle Membrane Secretory Granule Growth Cone Cytoplasmic Vesicle Membrane Nuclear Membrane Extrinsic Component Of Endoplasmic Reticulum Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome	Nuclear Envelope Endoplasmic Reticulum Endoplasmic Reticulum Lumen Nuclear Membrane Extracellular Exosome
	Molecular Function	Protein Binding ATP Binding Cytoskeletal Protein Binding ATPase Activity Kinesin Binding Identical Protein Binding Unfolded Protein Binding Misfolded Protein Binding	Protein Binding ATP Binding ATPase Activity Kinesin Binding Identical Protein Binding
	Biological Process	Protein Deneddylation Response To Oxidative Stress Organelle Organization Nuclear Envelope Organization Cell Adhesion Neuron Projection Development Protein Localization To Nucleus Wound Healing, Spreading Of Cells Intermediate Filament Cytoskeleton Organization Synaptic Vesicle Transport Chaperone Cofactor-dependent Protein Refolding Regulation Of Dopamine Uptake Involved In Synaptic Transmission Chaperone-mediated Protein Folding ER-associated Misfolded Protein Catabolic Process Nuclear Membrane Organization Chaperone-mediated Protein Transport Positive Regulation Of Synaptic Vesicle Endocytosis Regulation Of Protein Localization To Cell Surface	Response To Unfolded Protein Endoplasmic Reticulum Organization Protein Localization To Nucleus Chaperone Cofactor-dependent Protein Refolding Nuclear Membrane Organization
Pathways		Cargo recognition for clathrin-mediated endocytosis	Cargo recognition for clathrin-mediated endocytosis
Drugs
Diseases		Primary torsion dystonia (PTD)
GWAS		Prostate cancer ( 29892016) Prostate cancer (advanced) ( 29892016) Prostate cancer (early onset) ( 29892016)
Interacting Genes		7 interacting genes: KRTAP10-7 LMNA LRRC7 MDFI SNCA TOR1AIP2 TOR1B	1 interacting genes: TOR1A
Entrez ID		1861	27348
HPRD ID		06897	16270
Ensembl ID		ENSG00000136827	ENSG00000136816
Uniprot IDs		B3KPA1 O14656	O14657
PDB IDs		5J1S 5J1T 6OIF
Enriched GO Terms of Interacting Partners?
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