CHMP3 and CHMP4B

Data Source:
HPRD (two hybrid)

		CHMP3	CHMP4B
Description		charged multivesicular body protein 3	charged multivesicular body protein 4B
Image
GO Annotations	Cellular Component	ESCRT III Complex Late Endosome Multivesicular Body Cytosol Plasma Membrane Cytoplasmic Vesicle Late Endosome Membrane Extracellular Exosome	ESCRT III Complex Nucleus Nuclear Envelope Cytoplasm Endosome Multivesicular Body Cytosol Cytoplasmic Side Of Plasma Membrane Membrane Coat Midbody Late Endosome Membrane Vesicle Extracellular Exosome
	Molecular Function	Protein Binding Phosphatidylcholine Binding Ubiquitin-specific Protease Binding	Protein Binding Identical Protein Binding Protein Homodimerization Activity Cadherin Binding
	Biological Process	Apoptotic Process Nucleus Organization Mitotic Metaphase Plate Congression Regulation Of Centrosome Duplication Protein Transport Endosomal Transport Macroautophagy Viral Life Cycle Endosome Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Late Endosome To Vacuole Transport Regulation Of Viral Process Protein Polymerization Multivesicular Body-lysosome Fusion Midbody Abscission Multivesicular Body Sorting Pathway Autophagosome Maturation Regulation Of Mitotic Spindle Assembly Negative Regulation Of Viral Release From Host Cell Positive Regulation Of Viral Release From Host Cell Regulation Of Exosomal Secretion Regulation Of Early Endosome To Late Endosome Transport	Mitotic Cytokinesis Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Vesicle Budding From Membrane Autophagy Nucleus Organization Mitotic Metaphase Plate Congression Exit From Mitosis Regulation Of Centrosome Duplication Endosomal Transport Macroautophagy Viral Life Cycle Nuclear Envelope Reassembly Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Maintenance Of Lens Transparency Viral Budding Via Host ESCRT Complex Viral Budding Regulation Of Viral Process Protein Polymerization Negative Regulation Of Cell Death Midbody Abscission Membrane Fission Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Negative Regulation Of Neuron Death Regulation Of Mitotic Spindle Assembly Positive Regulation Of Viral Release From Host Cell Negative Regulation Of Autophagosome Assembly
Pathways		Budding and maturation of HIV virion Macroautophagy Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex	Budding and maturation of HIV virion Macroautophagy Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex
Drugs
Diseases
GWAS		Adult body size ( 32376654) Glomerular filtration rate in chronic kidney disease ( 26420894) Nicotine dependence symptom count ( 25555482)	Feeling nervous ( 29500382) Loneliness ( 27629369) Offspring birth weight ( 31043758) Refractive error ( 32231278) Stearic acid (18:0) levels ( 23362303)
Interacting Genes		13 interacting genes: APP CHMP2A CHMP2B CHMP4A CHMP4B FBXO7 IGFBP7 RAB11A SMAD1 SMAD5 STAMBP TNPO3 VAV2	16 interacting genes: CHMP1B CHMP3 CHMP4A CHMP4C CHMP5 CHMP6 EXOSC9 HIPK2 NOD2 PDCD6IP PIAS2 PLIN3 PTPN23 STAMBP UBE2I VPS4A
Entrez ID		51652	128866
HPRD ID		15650	16642
Ensembl ID		ENSG00000115561	ENSG00000101421
Uniprot IDs		Q9Y3E7	Q9H444
PDB IDs		2GD5 2XZE 3FRT 3FRV	3C3Q 3UM3 4ABM 5MK2
Enriched GO Terms of Interacting Partners?
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