ERGIC3 and LHFPL5

Data Source:
BioGRID (two hybrid)

		ERGIC3	LHFPL5
Description		ERGIC and golgi 3	LHFPL tetraspan subfamily member 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane COPII-coated ER To Golgi Transport Vesicle Integral Component Of Golgi Membrane Integral Component Of Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Plasma Membrane Membrane Integral Component Of Membrane Apical Plasma Membrane Stereocilium Tip
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum	Ion Transport Sensory Perception Of Sound Detection Of Mechanical Stimulus Involved In Sensory Perception Of Sound Detection Of Mechanical Stimulus Involved In Sensory Perception Auditory Receptor Cell Stereocilium Organization
Pathways
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Brain morphology (MOSTest) ( 32665545) Cholesterol, total ( 24097068 25961943 20686565) Height ( 28552196) Hip circumference adjusted for BMI ( 28552196) LDL cholesterol levels ( 32203549) Refractive error ( 32231278) Schizophrenia ( 28991256) Total cholesterol levels ( 28334899 30275531) Triglycerides ( 25961943) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494)
Interacting Genes		205 interacting genes: ABHD16A AGPAT4 AGTRAP AIG1 ALG10 AOC2 APOC3 APOD AQP10 AQP2 AQP3 ASGR1 BCL2L1 BET1 BIK BNIP3 BTN2A2 BUD31 C14orf180 C2 C3orf52 C4orf3 CCDC167 CCR2 CCR4 CCR8 CD207 CD302 CD81 CDIPT CDS2 CFHR5 CHRM4 CIAO2A CLCA4 CLDN19 CLDN8 CLDND2 CMTM5 CNIH1 CNIH3 COL4A5 COX20 CTSA CTXN3 CXorf66 CYB561 CYB561D2 CYBC1 CYP4F2 DEFB103A DEFB103B EBP EMC6 EMP1 EMP3 ENTPD3 ERGIC1 EXTL1 F2RL1 FA2H FAM3C FAXDC2 FETUB FIS1 FKBP8 FXYD2 FXYD3 FXYD6 GAST GIMAP1 GIMAP5 GJB2 GPM6B GPR151 GPR35 GPR37 GYPA HHATL HMOX1 HMOX2 IFITM3 IGFBP5 ITGAM JAGN1 KCNK1 LHFPL5 LPAR3 LPCAT2 MARCHF2 MARCHF5 MFF MFSD6 MIP MS4A13 MYADM NDRG4 NDUFB6 NEU1 NINJ2 NKG7 NRG4 NRM NSG1 ORMDL1 ORMDL3 PAQR5 PAQR7 PEX11G PEX16 PGAP2 PLLP PLP1 PLPP4 PMP22 POMGNT1 RFT1 RHAG RTP2 RUSF1 SCARB2 SCD SEC22B SEC23A SELENOK SERP2 SFXN5 SLC13A3 SLC1A1 SLC29A2 SLC35A1 SLC35A4 SLC35B2 SLC35B4 SLC38A7 SLC41A1 SLC41A2 SLC49A3 SMAGP SMCO4 SMIM1 SMIM3 SNORC SPN STATH STX12 STX1B STX3 STX8 SYNGR1 SYNJ2BP SYS1 TAP1 TECR TF THBD TM4SF4 TMEM100 TMEM107 TMEM109 TMEM120B TMEM128 TMEM141 TMEM14A TMEM14B TMEM179B TMEM203 TMEM218 TMEM222 TMEM229B TMEM243 TMEM42 TMEM60 TMEM65 TMEM86A TMEM86B TMEM97 TMUB2 TNFRSF10C TOMM6 TRAM1L1 TRARG1 TRIM32 TSPAN33 TSPO2 UBE2D3 UBIAD1 UNC50 UNC93B1 VAMP1 VAMP2 VAMP3 VAMP4 VKORC1L1 VMP1 VSTM1 VTI1B YIF1A YIPF1 YIPF2 YIPF4 YIPF6 ZDHHC15 ZDHHC21 ZFPL1	127 interacting genes: ADGRG3 APOL3 AQP2 AQP6 AQP9 BTN2A2 C14orf180 C1GALT1 C3orf52 C5orf46 CD37 CD53 CD72 CD79A CD81 CDS2 CERS4 CLCN7 CLDN22 CLDN5 CLDND2 CLEC14A CMTM7 CREB3 CREB3L1 CTXN3 CXCL16 CYB561 DAGLA ELOVL4 EMP1 EMP3 ENTPD3 ERG28 ERGIC3 FAM209A FCGR1A FFAR2 FNDC9 FXYD6 GGT7 GJA8 GJB2 GJB3 GJB4 GJB6 GPR152 GPR37L1 GPR42 GPRC5D GPX8 HAS3 HLA-DQA2 INSIG2 ITGB2 JAGN1 KASH5 KCNK5 KIR2DL3 KTN1 LAT LIME1 LMNA LNPEP LPAR3 LRRC25 LRRC4C MFF MFSD5 MIP MS4A13 MTIF3 NINJ2 NIPAL4 NKG7 NRG4 PDZK1IP1 PLLP PLP1 PLP2 RMDN3 RPRM RUSF1 SAR1A SEC22A SEC22B SERP1 SERP2 SERTM1 SLC16A2 SLC34A2 SLC35A1 SLC35B4 SLC35C2 SLC41A1 SMIM1 SYNJ2BP TEX264 TFRC TIMMDC1 TM4SF18 TM4SF4 TMEM100 TMEM107 TMEM128 TMEM201 TMEM218 TMEM229B TMEM248 TMEM254 TMEM31 TMEM42 TMEM50B TMEM52B TMEM60 TMEM86A TMEM97 TMX1 TMX2 TRARG1 TSPAN33 TSPAN7 TSPO UBIAD1 VAMP3 VMA21 ZDHHC15
Entrez ID		51614	222662
HPRD ID		15306	13989
Ensembl ID		ENSG00000125991	ENSG00000197753
Uniprot IDs		A2TJK5 Q9Y282	Q8TAF8
PDB IDs
Enriched GO Terms of Interacting Partners?
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