RAB14 and SH3BP5L

Data Source:
BioGRID (two hybrid)

		RAB14	SH3BP5L
Description		RAB14, member RAS oncogene family	SH3 binding domain protein 5 like
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Lysosome Lysosomal Membrane Early Endosome Late Endosome Rough Endoplasmic Reticulum Golgi Stack Trans-Golgi Network Cytosol Plasma Membrane Cilium Endomembrane System Trans-Golgi Network Transport Vesicle Early Endosome Membrane Nuclear Outer Membrane-endoplasmic Reticulum Membrane Network Intracellular Membrane-bounded Organelle Phagocytic Vesicle Perinuclear Region Of Cytoplasm Recycling Endosome Recycling Endosome Membrane Extracellular Exosome Tertiary Granule Membrane	Cytoplasm
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding Myosin V Binding	Protein Kinase Inhibitor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Phosphatidylinositol Biosynthetic Process Intracellular Protein Transport Golgi To Endosome Transport Fibroblast Growth Factor Receptor Signaling Pathway Vesicle-mediated Transport Endocytic Recycling Regulation Of Protein Localization Defense Response To Bacterium Neutrophil Degranulation Regulation Of Embryonic Development Intracellular Transport Phagolysosome Assembly Involved In Apoptotic Cell Clearance	Intracellular Signal Transduction Negative Regulation Of Protein Tyrosine Kinase Activity
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Synthesis of PIPs at the plasma membrane Neutrophil degranulation RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Immune reponse to smallpox (secreted IFN-alpha) ( 22610502)	Lead levels ( 26025379)
Interacting Genes		12 interacting genes: ADRB2 APP CHM EXOC5 FAM71C OCRL OPTN RAB11FIP5 RBSN RUFY1 SH3BP5L SMURF2	10 interacting genes: CEP57 EMC2 FAM161B NINL PLEKHA5 RAB11B RAB14 RAB25 SUOX YWHAG
Entrez ID		51552	80851
HPRD ID		06693	13887
Ensembl ID		ENSG00000119396	ENSG00000175137
Uniprot IDs		A0A024R845 P61106	A0A024R0T2 Q7L8J4
PDB IDs		1Z0F 4D0G 4DRZ
Enriched GO Terms of Interacting Partners?
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