LARS1 and MIR138-2

Data Source:
BioGRID (unspecified method)

		LARS1	MIR138-2
Description		leucyl-tRNA synthetase 1	microRNA 138-2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosome Endoplasmic Reticulum Cytosol Endomembrane System Nuclear Body Aminoacyl-tRNA Synthetase Multienzyme Complex
	Molecular Function	Aminoacyl-tRNA Editing Activity Glutamine-tRNA Ligase Activity Leucine-tRNA Ligase Activity GTPase Activator Activity Protein Binding ATP Binding
	Biological Process	TRNA Aminoacylation For Protein Translation Glutaminyl-tRNA Aminoacylation Leucyl-tRNA Aminoacylation Regulation Of Cell Size Positive Regulation Of TOR Signaling Cellular Response To Amino Acid Starvation Positive Regulation Of GTPase Activity Cellular Response To Amino Acid Stimulus Cellular Response To Leucine Aminoacyl-tRNA Metabolism Involved In Translational Fidelity Positive Regulation Of TORC1 Signaling Cellular Response To Leucine Starvation	Gene Silencing By MiRNA
Pathways		Selenoamino acid metabolism Cytosolic tRNA aminoacylation
Drugs		Leucine
Diseases
GWAS
Interacting Genes		55 interacting genes: CDC42 EEF1G ESR1 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR128-1 MIR128-2 MIR138-2 MIR15A MIR15B MIR17 MIR18A MIR18B MIR199A1 MIR19B1 MIR19B2 MIR200A MIR205 MIR206 MIR20B MIR21 MIR214 MIR221 MIR25 MIR29A MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR451A MIR7-1 MIR7-2 MIR9-1 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I SUMO2	87 interacting genes: AIMP1 AIMP2 APOBEC3B C1QBP CELF1 CPSF1 CPSF6 CRTAP CSTF3 DARS1 DDX1 DDX21 DDX23 DDX3X DDX49 DHX36 DHX37 EIF2AK2 EPRS1 ESRP1 FUS G3BP2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LRPPRC MARS1 MATR3 MSI2 NOL6 NONO NUFIP2 PATL1 PDCD11 PTBP1 PTBP3 PUF60 PUM1 QARS1 RARS1 RBFOX2 RBM14 RBM4 RTCA RTCB SF3A1 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 SUGP2 SYMPK SYNCRIP TAF15 TRA2A TRA2B TRIM26 TUT7 U2SURP UPF1 USP36 UTP20 YBX1 YBX2 YBX3 ZFR ZNF106
Entrez ID		51520	406930
HPRD ID		01042
Ensembl ID		ENSG00000133706	ENSG00000207649
Uniprot IDs		A0A6I8PL42 B4DER1 B4E266 Q9P2J5
PDB IDs		2WFD 6LPF 6LR6
Enriched GO Terms of Interacting Partners?
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