CHMP5 and RPL38

Data Source:
HPRD (two hybrid)

		CHMP5	RPL38
Description		charged multivesicular body protein 5	ribosomal protein L38
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GO Annotations	Cellular Component	Nucleus Multivesicular Body Cytosol Endosome Membrane Extracellular Exosome	Cytosol Focal Adhesion Postsynaptic Density Cytosolic Large Ribosomal Subunit Eukaryotic 80S Initiation Complex Polysomal Ribosome
	Molecular Function	Protein Binding Cadherin Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding
	Biological Process	Regulation Of Receptor Recycling Vesicle Budding From Membrane Nucleus Organization Lysosome Organization Mitotic Metaphase Plate Congression Endosome To Lysosome Transport Regulation Of Centrosome Duplication Protein Transport Endosomal Transport Viral Life Cycle Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Midbody Abscission Cellular Response To Lipopolysaccharide Cellular Response To Muramyl Dipeptide Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Assembly ESCRT III Complex Disassembly	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Skeletal System Development Ossification Cytoplasmic Translation Translation Translational Initiation Regulation Of Translation SRP-dependent Cotranslational Protein Targeting To Membrane Sensory Perception Of Sound Viral Transcription Ribonucleoprotein Complex Assembly 90S Preribosome Assembly Middle Ear Morphogenesis Axial Mesoderm Development
Pathways		Budding and maturation of HIV virion Endosomal Sorting Complex Required For Transport (ESCRT)	L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Erectile dysfunction and prostate cancer treatment ( 20932654)	Depression in smokers ( 30219690) Polymyositis ( 26362759)
Interacting Genes		16 interacting genes: APPBP2 CHMP1B CHMP4A CHMP4B GTF3A MITD1 NOD2 PDCD10 RPL38 SMARCA4 STAMBP URGCP VPS4B VTA1 ZNF142 ZNF91	5 interacting genes: AP2M1 BCCIP CHMP5 LILRB3 PTEN
Entrez ID		51510	6169
HPRD ID		15408	16048
Ensembl ID		ENSG00000086065	ENSG00000172809
Uniprot IDs		Q9NZZ3	A0A024R8P8 P63173
PDB IDs		2LXM 3ULY 3UM0 3UM1 3UM2 4TXR	4UG0 4V6X 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6LQM 6LSR 6LSS 6LU8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6SXO 6W6L 6XA1 6Y0G 6Y2L 6Y57 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO
Enriched GO Terms of Interacting Partners?
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