REV1 and POLL

Data Source:
HPRD (in vivo)

		REV1	POLL
Description		REV1 DNA directed polymerase	DNA polymerase lambda
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GO Annotations	Cellular Component	Nucleoplasm	Nucleus Nucleoplasm
	Molecular Function	Damaged DNA Binding DNA-directed DNA Polymerase Activity Protein Binding Deoxycytidyl Transferase Activity Metal Ion Binding	DNA Binding DNA-directed DNA Polymerase Activity Metal Ion Binding 5'-deoxyribose-5-phosphate Lyase Activity
	Biological Process	DNA Replication Response To UV Translesion Synthesis Error-prone Translesion Synthesis Error-free Translesion Synthesis	Double-strand Break Repair Via Homologous Recombination DNA Replication Base-excision Repair, Gap-filling Nucleotide-excision Repair Double-strand Break Repair Via Nonhomologous End Joining Somatic Hypermutation Of Immunoglobulin Genes DNA Biosynthetic Process
Pathways		Translesion synthesis by REV1 Translesion synthesis by POLK Translesion synthesis by POLI Termination of translesion DNA synthesis	Nonhomologous End-Joining (NHEJ)
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)
Interacting Genes		13 interacting genes: CLK1 FAAP20 FHL2 MAD2L2 POLD3 POLDIP2 POLH POLI POLK POLL REV3L TSC22D2 UBC	40 interacting genes: APP CCNDBP1 CDK2 CMTM5 FAM9B FSD2 GOLGA6L9 HMBOX1 HUWE1 KRT16 KRT19 KRT27 KRT40 KRTAP10-3 KRTAP10-7 LCN2 LDOC1 MAGEA12 MAGEA2 MAGEA2B MAL2 MCC MDFI PCNA PICK1 PNMA1 PRKD3 REV1 RPA1 SSX2IP TFCP2 TFIP11 TNFRSF10D TRIM23 UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2H ZRANB1
Entrez ID		51455	27343
HPRD ID		16202	09394
Ensembl ID		ENSG00000135945	ENSG00000166169
Uniprot IDs		Q49AI5 Q9UBZ9	A8K860 B4DE17 Q9UGP5
PDB IDs		2EBW 2LSI 2LSK 2LSY 2N1G 3GQC 3VU7 4BA9 4EXT 4GK0 4GK5 5VZM 6ASR 6AXD	1NZP 1RZT 1XSL 1XSN 1XSP 2BCQ 2BCR 2BCS 2BCU 2BCV 2GWS 2JW5 2PFN 2PFO 2PFP 2PFQ 3C5F 3C5G 3HW8 3HWT 3HX0 3MDA 3MDC 3MGH 3MGI 3PML 3PMN 3PNC 3UPQ 3UQ0 3UQ2 4FO6 4K4G 4K4H 4K4I 4X5V 4XA5 4XQ8 4XRH 4XUS 5CA7 5CB1 5CHG 5CJ7 5CP2 5CR0 5CWR 5DDM 5DDY 5DKW 5III 5IIJ 5IIK 5IIL 5IIM 5IIN 5IIO 5W4G
Enriched GO Terms of Interacting Partners?
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