HPCAL4 and AQP4

Data Source:
BioGRID (two hybrid)

		HPCAL4	AQP4
Description		hippocalcin like 4	aquaporin 4
Image		No pdb structure
GO Annotations	Cellular Component		Extracellular Region Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Endosome Membrane Integral Component Of Membrane Basolateral Plasma Membrane Sarcolemma Astrocyte End-foot
	Molecular Function	Calcium Channel Regulator Activity Calcium Ion Binding Protein Binding Protein C-terminus Binding Protein Domain Specific Binding	Protein Binding Water Channel Activity
	Biological Process	Signal Transduction Central Nervous System Development	Renal Water Homeostasis Water Transport Cellular Water Homeostasis Water Homeostasis Multicellular Organismal Water Homeostasis Protein Homotetramerization Transmembrane Transport Cellular Response To Interferon-gamma Cerebrospinal Fluid Circulation
Pathways			Vasopressin regulates renal water homeostasis via Aquaporins Passive transport by Aquaporins
Drugs
Diseases
GWAS		Bone mineral density (Ward's triangle area) ( 27397699)	Blood urea nitrogen levels ( 31152163) Chronic kidney disease ( 31152163) Creatinine levels ( 29403010) Estimated glomerular filtration rate ( 31152163 30604766) Glomerular filtration rate ( 29403010) Metabolite levels ( 23823483)
Interacting Genes		16 interacting genes: ANKRD33 AQP4 CDSN CEACAM6 DTX2 F3 FAM131C LITAF MSRA SCMH1 SPRED1 TEX13B TRPM5 TSC22D3 TTC12 UBE3A	7 interacting genes: AP2M1 AP3M1 CREB3 CSNK2A1 CSNK2A2 GJA8 HPCAL4
Entrez ID		51440	361
HPRD ID		17113	02631
Ensembl ID		ENSG00000116983	ENSG00000171885
Uniprot IDs		B4DGW9 Q9UM19	A0A5F9ZHR4 F1DSG4 P55087 V9PBN7
PDB IDs			3GD8
Enriched GO Terms of Interacting Partners?
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