TRAPPC4 and PRSS23

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TRAPPC4	PRSS23
Description		trafficking protein particle complex subunit 4	serine protease 23
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Golgi Stack Cytosol Synaptic Vesicle TRAPP Complex Dendrite Synapse Postsynaptic Membrane	Nucleus Endoplasmic Reticulum Lumen Extracellular Exosome
	Molecular Function	Protein Binding	Serine-type Endopeptidase Activity Protein Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Autophagy Dendrite Development COPII Vesicle Coating	Proteolysis Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways		COPII-mediated vesicle transport Syndecan interactions RAB GEFs exchange GTP for GDP on RABs	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs		S-palmitoyl-L-cysteine
Diseases
GWAS			Blood urea nitrogen levels ( 31152163) Chronic obstructive pulmonary disease ( 30804561) FEV1 ( 30804560) Heel bone mineral density ( 30598549 28869591) Intraocular pressure ( 29617998 29785010) Lung function (FEV1) ( 28166213) Lung function (FEV1/FVC) ( 30804560) Peak expiratory flow ( 30804560)
Interacting Genes		10 interacting genes: APP PRSS23 SDC2 TFIP11 TRAPPC11 TRAPPC12 TRAPPC2 TRAPPC2L TRAPPC3L TRAPPC8	26 interacting genes: ACTG1 APP B2M CHP1 EFNA3 FXR1 GATD1 GRK6 HSPA4 MAPK8IP2 NCAPD3 NIPBL NOC4L ODF2L PDPK1 PHF23 PPIA RACGAP1 RECQL4 RPL4P5 SEC11C SHMT1 SLC25A6 TCF12 TMEM222 TRAPPC4
Entrez ID		51399	11098
HPRD ID		18220	07149
Ensembl ID		ENSG00000196655	ENSG00000150687
Uniprot IDs		B4DF86 E9PKS9 E9PQE8 J3KP27 Q9Y296	O95084
PDB IDs		2J3T 2JSN 2ZMV
Enriched GO Terms of Interacting Partners?
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