GOLM1 and EIF2B3

Data Source:
HPRD (two hybrid)

		GOLM1	EIF2B3
Description		golgi membrane protein 1	eukaryotic translation initiation factor 2B subunit gamma
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Endoplasmic Reticulum Lumen Golgi Apparatus Integral Component Of Plasma Membrane	Cytoplasm Cytosol Eukaryotic Translation Initiation Factor 2B Complex Guanyl-nucleotide Exchange Factor Complex
	Molecular Function	Protein Binding	Translation Initiation Factor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding Translation Factor Activity, RNA Binding
	Biological Process	Nucleus Organization Regulation Of Lipid Metabolic Process Post-translational Protein Modification Cellular Protein Metabolic Process	Cytoplasmic Translational Initiation Translational Initiation Response To Heat Response To Glucose Oligodendrocyte Development Hippocampus Development Response To Peptide Hormone Regulation Of Catalytic Activity T Cell Receptor Signaling Pathway
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation	Recycling of eIF2:GDP
Drugs
Diseases			Leukoencephalopathy with vanishing white matter; Vanishing white matter disease; Childhood ataxia with diffuse central nervous system hypomyelination (CACH); Cree leukoencephalopathy (CLE)
GWAS		Blood protein levels ( 30072576) Logical memory (delayed recall) in normal cognition ( 29274321)	Platelet distribution width ( 32888494)
Interacting Genes		76 interacting genes: ABI3 AIG1 ANKRD46 ASPH B3GNT4 BCL2L1 C1orf174 C1QL4 CDIPT CIAO1 CLDN4 CLDND2 CLK1 CNPY3 DCK DCTN2 DESI1 DEXI EFTUD2 EIF2B3 EIF3J ELAC2 FLOT1 FTH1 FUT9 GALNT15 GAST GEMIN7 GET3 GLB1 GRIK5 GUCA2A HGFAC HSD17B13 IGFBP5 INSIG2 JAGN1 KCNE3 LAT LSM12 MED22 MIP NDUFV2 NEU1 NINJ1 NIPSNAP3A NRSN2 PGRMC1 RACK1 RIPPLY2 RPA2 RPL13A SFTPC SLC13A5 SLC30A3 SLC35B2 SLC40A1 SLC5A4 SLCO3A1 ST6GAL2 STRIT1 SYT1 TF THSD7A TMEM109 TMEM140 TMEM147 TMEM176A TMEM86B TMEM98 TMPO TMUB1 TMUB2 TSG101 VSTM1 ZFAND3	5 interacting genes: EIF2S1 EIF2S2 GOLM1 NDUFB8 STC2
Entrez ID		51280	8891
HPRD ID		08428	09379
Ensembl ID		ENSG00000135052	ENSG00000070785
Uniprot IDs		B3KNK9 Q8NBJ4	Q9HA31 Q9NR50
PDB IDs			6CAJ 6EZO 6K71 6K72 6O81 6O85 6O9Z
Enriched GO Terms of Interacting Partners?
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