DUSP13 and SH2B2

Data Source:
BioGRID (two hybrid)

		DUSP13	SH2B2
Description		dual specificity phosphatase 13	SH2B adaptor protein 2
Image
GO Annotations	Cellular Component		Cytoplasm Cytosol Plasma Membrane
	Molecular Function	Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Phosphatase Activity Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity	Transmembrane Receptor Protein Tyrosine Kinase Adaptor Activity Protein Binding Signaling Adaptor Activity SH2 Domain Binding
	Biological Process	Protein Dephosphorylation Spermatogenesis Dephosphorylation Peptidyl-tyrosine Dephosphorylation Meiotic Cell Cycle	Blood Coagulation Insulin Receptor Signaling Pathway Intracellular Signal Transduction Antigen Receptor-mediated Signaling Pathway B Cell Receptor Signaling Pathway
Pathways			Regulation of KIT signaling Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Body mass index ( 29273807) HDL cholesterol levels ( 32203549) Height ( 31562340)	Type 2 diabetes ( 31049640)
Interacting Genes		14 interacting genes: ACVR1 CALCOCO1 CARD9 CCDC85B HOOK2 HSF2BP INCA1 LMNA PLEKHG4 SH2B2 SMURF1 TGFBR1 TRAF1 ZRANB1	42 interacting genes: AKT1 ASB6 BTK CBL CLK1 CLK3 DUSP13 EGFR EPOR ERBB2 ERBB4 FAM124B FAM90A1 FYN GRB2 HCK IL36RN INSR JAK1 JAK2 JAK3 KIT LMO3 LYN MAGEH1 MCRS1 MET MTDH NTRK1 NTRK2 PDLIM7 PLEKHA3 RAB6B SH2B1 SHC1 SORBS1 SYK TLE5 TLNRD1 USP2 ZNF414 ZNF417
Entrez ID		51207	10603
HPRD ID		13251	16097
Ensembl ID		ENSG00000079393	ENSG00000160999
Uniprot IDs		Q6B8I1 Q9UII6	O14492
PDB IDs		2GWO 2PQ5 5XJV	1Q2H
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?