DYNC1LI1 and NOP56

Data Source:
BioGRID (two hybrid)

		DYNC1LI1	NOP56
Description		dynein cytoplasmic 1 light intermediate chain 1	NOP56 ribonucleoprotein
Image			No pdb structure
GO Annotations	Cellular Component	Kinetochore Condensed Chromosome Kinetochore Spindle Pole Centrosome Cytosol Cytoplasmic Dynein Complex Microtubule Plasma Membrane Membrane Secretory Granule Membrane Ficolin-1-rich Granule Membrane	Fibrillar Center Nucleoplasm Nucleolus Sno(s)RNA-containing Ribonucleoprotein Complex Cytoplasm Membrane Box C/D RNP Complex Small-subunit Processome Pre-snoRNP Complex
	Molecular Function	RNA Binding Motor Activity Protein Binding ATP Binding GTP Binding GDP Binding Dynein Heavy Chain Binding	RNA Binding Protein Binding SnoRNA Binding Cadherin Binding Histone Methyltransferase Binding
	Biological Process	Microtubule Cytoskeleton Organization Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Microtubule-based Movement Cell Cycle Viral Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Neutrophil Degranulation Cell Division Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint	RRNA Processing
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion HSP90 chaperone cycle for steroid hormone receptors (SHR) RHO GTPases Activate Formins Neutrophil degranulation COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase HCMV Early Events Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation	Association of TriC/CCT with target proteins during biosynthesis rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases			Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
GWAS		Bitter taste perception (6-n-propylthiouracil) in obesity with metabolic syndrome ( 31005965) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
Interacting Genes		7 interacting genes: BRCA2 IKBKG NOP56 NUP85 PGAM2 RAB4A REL	8 interacting genes: BMPR2 CSNK2A1 DYNC1LI1 KLF6 PTEN SDCBP2 TCOF1 UBE2I
Entrez ID		51143	10528
HPRD ID		10917	10119
Ensembl ID		ENSG00000144635	ENSG00000101361
Uniprot IDs		E9PHI6 Q9Y6G9	O00567
PDB IDs		6B9H 6PSE
Enriched GO Terms of Interacting Partners?
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