POLR1D and DNAJB6

Data Source:
BioGRID (two hybrid)

		POLR1D	DNAJB6
Description		RNA polymerase I and III subunit D	DnaJ heat shock protein family (Hsp40) member B6
Image		No pdb structure
GO Annotations	Cellular Component	RNA Polymerase III Complex RNA Polymerase I Complex	Nucleus Nucleoplasm Cytosol Membrane Z Disc Perinuclear Region Of Cytoplasm
	Molecular Function	DNA Binding DNA-directed 5'-3' RNA Polymerase Activity Protein Binding Protein Dimerization Activity	ATPase Activator Activity Protein Binding Heat Shock Protein Binding Unfolded Protein Binding Chaperone Binding
	Biological Process	Transcription, DNA-templated	Protein Folding Positive Regulation Of ATPase Activity Regulation Of Protein Localization Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Intermediate Filament Organization Negative Regulation Of Inclusion Body Assembly Regulation Of Cellular Response To Heat
Pathways		Cytosolic sensors of pathogen-associated DNA NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase III Chain Elongation RNA Polymerase I Transcription Termination RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter	Regulation of HSF1-mediated heat shock response
Drugs
Diseases		Treacher Collins syndrome
GWAS		Body mass index ( 26426971)	Body mass index ( 28552196) Retinal detachment or retinal break ( 31816047) Waist circumference ( 28552196)
Interacting Genes		15 interacting genes: CDC25A CRKL DDIT3 DNAJB4 DNAJB6 E2F4 GRB2 HAX1 MAGEA11 MRPL12 NFKBIB NR3C1 POLR1C POLR1G PXN	23 interacting genes: ANKRD1 APP ASAP1 BRMS1 CAND2 DYSF KRT18 MAP3K1 MLF1 MLF2 MRTO4 MYBPC1 MYOM1 PGM1 PIK3CA POLR1D PTEN SGCG SKAP2 SUPT6H TTN TUBGCP3 USP8
Entrez ID		51082	10049
HPRD ID		17877	07107
Ensembl ID		ENSG00000186184	ENSG00000105993
Uniprot IDs		A0A087WTY1 P0DPB5 P0DPB6	A0A0J9YX62 O75190
PDB IDs			6U3R 6U3S
Enriched GO Terms of Interacting Partners?
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