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TMX2 and VAPA
Data Source:
BioGRID
(two hybrid)
TMX2
VAPA
Description
thioredoxin related transmembrane protein 2
VAMP associated protein A
Image
GO Annotations
Cellular Component
Mitochondrion
Endoplasmic Reticulum Membrane
Integral Component Of Membrane
Mitochondrial Membrane
Membrane-bounded Organelle
Mitochondria-associated Endoplasmic Reticulum Membrane
Golgi Membrane
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Plasma Membrane
Bicellular Tight Junction
Integral Component Of Membrane
Nuclear Membrane
Vesicle
Azurophil Granule Membrane
Perinuclear Region Of Cytoplasm
Endoplasmic Reticulum Exit Site
Molecular Function
Protein Binding
Disulfide Oxidoreductase Activity
Identical Protein Binding
Protein Binding
Microtubule Binding
Protein Domain Specific Binding
FFAT Motif Binding
Cadherin Binding
Protein Heterodimerization Activity
Biological Process
Brain Development
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Endoplasmic Reticulum Organization
Cell Death
Viral Process
Sphingolipid Biosynthetic Process
Neuron Projection Development
Protein Folding In Endoplasmic Reticulum
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Neutrophil Degranulation
Positive Regulation By Host Of Viral Release From Host Cell
Negative Regulation By Host Of Viral Genome Replication
Positive Regulation By Host Of Viral Genome Replication
Membrane Fusion
Protein Localization To Endoplasmic Reticulum
COPII-coated Vesicle Budding
Pathways
Sphingolipid de novo biosynthesis
Neutrophil degranulation
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases
GWAS
Autism spectrum disorder or schizophrenia (
28540026
)
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Neuroticism (
29255261
)
Problematic alcohol use (
32451486
)
Reticulocyte count (
32888494
)
Schizophrenia (
25056061
29483656
)
Diverticular disease (
30177863
)
FEV1 (
30804560
)
Heel bone mineral density (
30598549
)
Lung function (FEV1/FVC) (
30804560
)
Metabolite levels (
23823483
)
Peak expiratory flow (
30804560
)
Pulmonary function (smoking interaction) (
23284291
)
Interacting Genes
164 interacting genes:
AGPAT3
AGPAT4
AGPAT5
AIG1
AQP6
ARV1
ASGR1
ASPH
ATXN1
BDKRB1
BET1
BNIP1
BNIP2
BNIP3
BRICD5
BTN2A2
C2CD2L
C3orf52
CCDC167
CCL2
CD81
CDIPT
CDS2
CMTM7
COL8A2
COMMD8
COX20
CTSA
CTXN3
CXCL16
CXorf66
CYBC1
CYP4F2
DERL1
DGAT2L6
EMD
EMP3
F2RL1
FA2H
FAM177A1
FAM241B
FAM3C
FAXDC2
FDFT1
FUNDC2
FXYD6-FXYD2
GIMAP1
GIMAP5
GJB2
HACD2
HHATL
HMOX2
HSD17B11
HSD17B13
HSD3B7
HTATIP2
IER3
IER3IP1
IGFBP5
INSIG2
ITGAM
LEPROT
LEPROTL1
LHFPL5
LRAT
MALL
MFF
MFSD14B
MGLL
MGST3
MIP
MLN
MS4A1
MTNR1A
NAT8
NDUFA3
NINJ2
NRM
NSDHL
NSG1
ORMDL2
OTULINL
PAEP
PEDS1-UBE2V1
PEX16
PKMYT1
PLP2
PNLIPRP1
PRAF2
PRB1
PTAFR
PTPN9
RABAC1
REEP2
REEP4
RFT1
RNF24
RTP2
RUSF1
SACM1L
SCAMP5
SCD
SELENOK
SERF1A
SERF1B
SERP2
SFT2D1
SFXN1
SFXN3
SLC22A18
SLC22A2
SLC29A2
SLC35A1
SMAGP
SMCO4
SMIM1
STATH
STX12
STX3
STX7
THBD
THSD7B
TMBIM6
TMEM115
TMEM120A
TMEM120B
TMEM121
TMEM128
TMEM140
TMEM14B
TMEM14C
TMEM176A
TMEM201
TMEM203
TMEM208
TMEM222
TMEM239
TMEM254
TMEM31
TMEM50B
TMEM51
TMEM65
TMEM71
TMEM86B
TMEM97
TPRG1
TRAM1L1
TREX1
TSNARE1
TSPAN2
TVP23B
UBE2J1
UNC93A
VAMP1
VAMP3
VAMP4
VAMP5
VAPA
VAPB
WFDC2
YIF1A
YIPF1
YIPF2
YIPF6
39 interacting genes:
ADGRG7
ADRB2
APOD
APP
AQP6
CACNG1
CD79A
CYB561
CYBRD1
EBAG9
EBP
EGFR
ERBB2
GKN1
HSD17B11
HSD17B13
JAGN1
KCNB1
LEPROTL1
NSF
OPRM1
OSBP
PGRMC2
RETREG3
RMDN2
SCN3B
SEC11C
SIK1
SLC16A7
SLC35B1
TMEM229B
TMEM35A
TMEM86B
TMIE
TMX2
USP20
VAMP1
VAMP2
ZBTB22
Entrez ID
51075
9218
HPRD ID
07159
09299
Ensembl ID
ENSG00000213593
ENSG00000101558
Uniprot IDs
Q9Y320
Q9P0L0
PDB IDs
2DJ0
2RR3
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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