MYEF2 and MIR221

Data Source:
BioGRID (unspecified method)

		MYEF2	MIR221
Description		myelin expression factor 2	microRNA 221
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Post-mRNA Release Spliceosomal Complex Ribonucleoprotein Complex	Extracellular Space Extracellular Vesicle
	Molecular Function	Single-stranded DNA Binding RNA Binding MRNA Binding	MRNA Binding Involved In Posttranscriptional Gene Silencing
	Biological Process	Regulation Of Transcription By RNA Polymerase II Myotube Differentiation Neuron Differentiation Regulation Of MRNA Stability Involved In Response To Oxidative Stress	Negative Regulation Of Cell Population Proliferation Response To Glucose Positive Regulation Of Epithelial Cell Migration Positive Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Interleukin-21 Production Negative Regulation Of Heterotypic Cell-cell Adhesion Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Positive Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation By Host Of Viral Genome Replication Positive Regulation Of Erythrocyte Differentiation Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Platelet-derived Growth Factor Receptor Signaling Pathway Positive Regulation Of Axon Regeneration Negative Regulation Of Inflammatory Response Positive Regulation Of Protein Kinase B Signaling Negative Regulation Of Cell Adhesion Molecule Production Negative Regulation Of Necroptotic Process Negative Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Negative Regulation Of Cytokine Production Involved In Inflammatory Response Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Schwann Cell Migration Negative Regulation Of Hematopoietic Stem Cell Proliferation Negative Regulation Of TRAIL-activated Apoptotic Signaling Pathway Negative Regulation Of Sprouting Angiogenesis Positive Regulation Of Wound Healing, Spreading Of Epidermal Cells Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Positive Regulation Of Vascular Associated Smooth Muscle Cell Migration Negative Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Positive Regulation Of Schwann Cell Proliferation Involved In Axon Regeneration Negative Regulation Of Vascular Associated Smooth Muscle Cell Differentiation Positive Regulation Of Vascular Associated Smooth Muscle Cell Dedifferentiation Negative Regulation Of Double-strand Break Repair
Pathways
Drugs
Diseases
GWAS		Skin pigmentation ( 28300201)
Interacting Genes		40 interacting genes: COG8 GOLGA2 LNX1 MIR128-2 MIR141 MIR15A MIR17 MIR19B1 MIR19B2 MIR200A MIR20A MIR20B MIR21 MIR221 MIR25 MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR363 MIR429 MIR9-1 MIR9-2 MIR93 MIRLET7A3 MIRLET7B MIRLET7D MIRLET7E MIRLET7F1 MIRLET7G MIRLET7I NFKBID OIP5 PLEKHG4 TEX11 TRAF1 TRIM23 ZRANB1	87 interacting genes: ADARB1 AIMP2 APOBEC3B AQR C1QBP CELF1 CPSF1 DARS1 DDX1 DDX21 DDX3X DHX36 EIF2AK2 EPRS1 ERAL1 FAM98A FIP1L1 FUS G3BP2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI1 MSI2 MYEF2 NOL6 NONO NUDT21 PDCD11 PLOD1 PRMT1 PTBP1 PTBP3 PUF60 PUM2 PURA QARS1 RARS1 RBFOX2 RBM14 RBM4 RTCB SART3 SF3A1 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SUGP2 SYNCRIP TAF15 TRA2A TRA2B TRIM25 U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZNF346
Entrez ID		50804	407006
HPRD ID		14794
Ensembl ID		ENSG00000104177	ENSG00000207870
Uniprot IDs		A0A024R5Q6 Q9P2K5
PDB IDs
Enriched GO Terms of Interacting Partners?
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