KCNK4 and RPL14

Data Source:
BioGRID (two hybrid)

		KCNK4	RPL14
Description		potassium two pore domain channel subfamily K member 4	ribosomal protein L14
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Potassium Channel Complex	Cytosol Postsynaptic Density Membrane Cytosolic Large Ribosomal Subunit Extracellular Exosome
	Molecular Function	Voltage-gated Ion Channel Activity Potassium Channel Activity Potassium Ion Leak Channel Activity Temperature-gated Cation Channel Activity Mechanosensitived Potassium Channel Activity	RNA Binding Structural Constituent Of Ribosome Protein Binding Cadherin Binding
	Biological Process	Potassium Ion Transport Memory Sensory Perception Of Pain Stabilization Of Membrane Potential Regulation Of Ion Transmembrane Transport Sensory Perception Of Temperature Stimulus Detection Of Mechanical Stimulus Involved In Sensory Perception Of Touch Cellular Response To Mechanical Stimulus Cellular Response To Fatty Acid Cellular Response To Alkaline PH Cellular Response To Temperature Stimulus Potassium Ion Transmembrane Transport	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay RRNA Processing Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription Ribosomal Large Subunit Biogenesis
Pathways		TWIK related potassium channel (TREK) Phase 4 - resting membrane potential	L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs			Artenimol
Diseases
GWAS		Crohn's disease ( 28067908) Sarcoidosis ( 22837380) Vitiligo ( 27723757)	Neuroticism ( 29255261)
Interacting Genes		3 interacting genes: DIDO1 ORMDL1 RPL14	7 interacting genes: FBXO7 KCNK4 KLF10 PEX5 PHLDA1 PTEN TLE6
Entrez ID		50801	9045
HPRD ID		12037	10617
Ensembl ID		ENSG00000182450	ENSG00000188846
Uniprot IDs		A0A024R5C7 Q2YDA1 Q9NYG8	P50914
PDB IDs		3UM7 4I9W 4RUE 4RUF 4WFE 4WFF 4WFG 4WFH	4UG0 4V6X 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6LQM 6LSR 6LSS 6LU8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6W6L 6XA1 6Y0G 6Y2L 6Y57 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO
Enriched GO Terms of Interacting Partners?
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