PAX4 and FBXO2

Data Source:
BioGRID (two hybrid)

		PAX4	FBXO2
Description		paired box 4	F-box protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleoplasm	Cytoplasm Endoplasmic Reticulum Cytosol SCF Ubiquitin Ligase Complex Organelle Membrane Dendritic Spine
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Sequence-specific Double-stranded DNA Binding	Amyloid-beta Binding Ubiquitin-protein Transferase Activity Protein Binding Carbohydrate Binding Ubiquitin Protein Ligase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Animal Organ Morphogenesis Cell Differentiation Endocrine Pancreas Development Anatomical Structure Development	Protein Polyubiquitination Cellular Protein Modification Process Proteolysis Glycoprotein Catabolic Process Negative Regulation Of Cell Population Proliferation Protein Ubiquitination Ubiquitin-dependent ERAD Pathway SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Ubiquitination Post-translational Protein Modification
Pathways			Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases		Maturity onset diabetes of the young (MODY)
GWAS		Fruit consumption ( 32066663) Left-handedness ( 32989287) Metabolite levels ( 23823483) Nonsyndromic cleft palate ( 31609978) Type 2 diabetes ( 32794382 29632382 26818947 32499647 22158537 30718926 23532257) Type 2 diabetes (adjusted for BMI) ( 29632382)
Interacting Genes		14 interacting genes: AURKA CABP5 EIF4A3 FBXO2 GMCL1 NAIF1 NECAB1 NFYC NME7 NRXN3 NTM NUTF2 PSMC1 UBL5	16 interacting genes: AHSG BACE1 BRAP ECPAS IGH ITGB1 PAX4 PFDN6 SKP1 STUB1 UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2L3 VSTM1
Entrez ID		5078	26232
HPRD ID		01333	06171
Ensembl ID		ENSG00000106331	ENSG00000116661
Uniprot IDs			Q9UK22
PDB IDs
Enriched GO Terms of Interacting Partners?
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