NUCB1 and SET

Data Source:
BioGRID (two hybrid)

		NUCB1	SET
Description		nucleobindin 1	SET nuclear proto-oncogene
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GO Annotations	Cellular Component	Extracellular Space Nucleus Early Endosome Endoplasmic Reticulum Lumen Rough Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi-associated Vesicle Cis-Golgi Network Trans-Golgi Network Membrane Golgi Cisterna Membrane Extracellular Exosome Extrinsic Component Of Golgi Membrane Lumenal Side Of Golgi Membrane	Chromatin Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Lipid Droplet Cytosol Protein-containing Complex Perinuclear Region Of Cytoplasm
	Molecular Function	G-protein Alpha-subunit Binding DNA Binding Guanyl-nucleotide Exchange Factor Activity Calcium Ion Binding Protein Binding	DNA Binding Chromatin Binding Protein Phosphatase Inhibitor Activity Protein Binding Protein Phosphatase Regulator Activity Histone Binding
	Biological Process	Small GTPase Mediated Signal Transduction Post-translational Protein Modification Cellular Protein Metabolic Process Regulation Of Catalytic Activity Response To Cisplatin Regulation Of Protein Targeting	DNA Replication Nucleosome Assembly Nucleosome Disassembly Viral Process Negative Regulation Of Phosphoprotein Phosphatase Activity Negative Regulation Of Histone Acetylation Regulation Of MRNA Stability Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Transcription, DNA-templated
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation	Condensation of Prophase Chromosomes HuR (ELAVL1) binds and stabilizes mRNA
Drugs		Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS			Axial length ( 24144296) Body mass index ( 26426971) Eating disorders (purging via substances) ( 23568457)
Interacting Genes		16 interacting genes: GNAI1 GNAI2 GNAI3 GNAO1 GNAS GNAZ HIVEP1 MYC NDN PTGS1 PTGS2 RBL1 REL SET SIRPA XPO1	68 interacting genes: ANP32A APEX1 APP CALM1 CDCA8 CDK5 CDK5R1 CDKN1A CHAF1A CHRM2 CHRM3 ELAVL1 ELF4 ENO1 EP300 ESR1 FAM111B FBXO7 FOS FOXO1 GZMA GZMK H1-1 H2BC1 H3-3A H3-4 H4-16 H4C14 HMGB2 IRF1 JUNB KLF5 KMT2A LGMN MDM2 MEOX2 MTERF1 NME1 NUCB1 NUPR1 PAX6 PIK3CG PPP2CA PPP2R1B PRKAR1A PTEN PTMA RAC1 REPIN1 SDCBP SETBP1 SGO1 SGO2 TAF1A TERF1 TERF2 TERF2IP TEX35 THAP7 TLE5 TREX1 TRIM55 TRIM63 UCHL5 XRCC6 ZNF17 ZNF438 ZNF85
Entrez ID		4924	6418
HPRD ID		03205	09023
Ensembl ID		ENSG00000104805	ENSG00000119335
Uniprot IDs		A8K7Q1 Q02818	A0A024R895 A0A0C4DFV9 Q01105 Q5VXV3
PDB IDs		1SNL	2E50
Enriched GO Terms of Interacting Partners?
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