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NME1 and NIF3L1
Data Source:
BioGRID
(two hybrid)
NME1
NIF3L1
Description
NME/NM23 nucleoside diphosphate kinase 1
NGG1 interacting factor 3 like 1
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Mitochondrial Outer Membrane
Centrosome
Cytosol
Intermediate Filament
Membrane
Ruffle Membrane
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Nucleus
Cytoplasm
Mitochondrion
Molecular Function
Magnesium Ion Binding
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
Single-stranded DNA Binding
RNA Binding
Deoxyribonuclease Activity
Nucleoside Diphosphate Kinase Activity
Protein Binding
ATP Binding
GTP Binding
Intermediate Filament Binding
Enzyme Binding
Identical Protein Binding
Gamma-tubulin Binding
Ribosomal Small Subunit Binding
Protein Binding
Transcription Factor Binding
Identical Protein Binding
Biological Process
Negative Regulation Of Myeloid Leukocyte Differentiation
Nucleoside Diphosphate Phosphorylation
GTP Biosynthetic Process
UTP Biosynthetic Process
CTP Biosynthetic Process
DNA Metabolic Process
Endocytosis
Lactation
Negative Regulation Of Cell Population Proliferation
Negative Regulation Of Gene Expression
Positive Regulation Of Neuron Projection Development
Response To Amine
Nucleobase-containing Small Molecule Interconversion
Hippocampus Development
Cell Differentiation
Response To Testosterone
Cellular Response To Drug
Regulation Of Apoptotic Process
Positive Regulation Of DNA Binding
Positive Regulation Of Epithelial Cell Proliferation
Response To CAMP
Cellular Response To Glucose Stimulus
Cellular Response To Fatty Acid
Neuron Differentiation
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Pathways
Interconversion of nucleotide di- and triphosphates
Drugs
Zinc
2'-Deoxyguanosine-5'-Triphosphate
Selenocysteine
2',3'-Dehydro-2',3'-Deoxy-Thymidine 5'-Diphosphate
Adenosine Phosphonoacetic Acid
Stavudine triphosphate
Thymidine-5'- Diphosphate
2'-Deoxyguanosine-5'-Diphosphate
2',3'-dideoxy-3'-fluoro-urididine-5'-diphosphate
Guanosine-5'-Diphosphate
3'-Deoxy 3'-Amino Adenosine-5'-Diphosphate
Zidovudine diphosphate
Copper
Zinc acetate
Zinc chloride
Zinc sulfate, unspecified form
Diseases
GWAS
Bipolar disorder (
31043756
)
Conjunctival UV autofluorescence (CUVAF) (
25590795
)
Metabolite levels (
23823483
)
Triptolide cytotoxicity (
26121980
)
Interacting Genes
31 interacting genes:
APEX1
AURKA
CCND3
FBXO24
FXR2
GORASP2
ITGB1
KSR1
LNX1
MIF
NIF3L1
NME2
NME3
NME4
NTAQ1
NUTF2
PID1
POLR1C
PRUNE1
RAC1
RORA
RORB
RRAD
SET
SMARCD1
SOX30
SREK1IP1
TERF1
TIAM1
TNPO2
TNPO3
93 interacting genes:
ALKBH4
AP5B1
APIP
ARPIN
BDKRB2
BEND7
C14orf119
CASP7
CCDC102B
CCDC85B
CDKN2B
CDKN2C
CDKN2D
COIL
COPS2
CUTC
CYRIB
DCDC2
DCTD
DCTPP1
DHPS
DMC1
DMRTB1
DTX2
DUSP23
DUSP29
DYNLT3
EIF4A3
EIF5A2
ENOX1
EPHB6
FLAD1
FXR2
GNMT
GRB2
IP6K3
KCNIP1
KCTD17
KCTD7
KCTD9
KRT15
KXD1
LAMTOR3
LMO2
LMO3
MAGEA11
MAPRE2
MLXIPL
NATD1
NEK6
NGB
NME1
NME7
NOL3
NUDT14
NUDT21
ORC5
PAFAH1B3
PAICS
PCBD1
PNMA1
POLR1C
PPIH
PRTFDC1
PTPA
RABAC1
RAD54B
RPIA
S100A1
SAT1
SEPTIN1
SNF8
SPG21
SSX2IP
STAT3
STK16
SULT1A2
SULT1A3
SULT2A1
SYT17
TCL1A
THOC7
TIFA
TRAF2
TRIM21
TRIM27
TRIP13
TSC22D4
TXN
VIM
YES1
YWHAQ
ZBED1
Entrez ID
4830
60491
HPRD ID
01131
10424
Ensembl ID
ENSG00000239672
ENSG00000196290
Uniprot IDs
A0A384MTW7
P15531
A0A024R3V5
A0A024R3V7
Q9GZT8
PDB IDs
1JXV
1UCN
2HVD
2HVE
3L7U
4ENO
5UI4
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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