NHLH2 and TAF1D

Data Source:
BioGRID (two hybrid)

		NHLH2	TAF1D
Description		nescient helix-loop-helix 2	TATA-box binding protein associated factor, RNA polymerase I subunit D
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Transcription Regulator Complex	Nucleoplasm RNA Polymerase Transcription Factor SL1 Complex Nucleolus Cytosol Centriolar Satellite Mitotic Spindle
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Activating Transcription Factor Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Protein Dimerization Activity Sequence-specific Double-stranded DNA Binding	DNA Binding Protein Binding Identical Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Apoptotic Process Central Nervous System Development Male Gonad Development Cell Migration In Hindbrain Cell Differentiation Ovulation Cycle Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of DNA-binding Transcription Factor Activity Male Mating Behavior	Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Positive Regulation Of Gene Expression, Epigenetic
Pathways			SIRT1 negatively regulates rRNA expression NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination
Drugs
Diseases
GWAS		Electrocardiographic traits ( 32602732) Heart rate variability traits (SDNN) ( 28610988) Metabolite levels ( 23823483)
Interacting Genes		7 interacting genes: HES1 KCNIP1 LMO3 MYF5 TAF1D TCF12 TCF4	24 interacting genes: CEP70 DDAH2 EZH2 FAF1 FAM20C FEZ1 HAP1 HSP90AB1 IMMT ING5 ITFG1 LRIF1 MCM3AP MCPH1 NGEF NHLH2 POLB PTN RPL36AL SMARCB1 TAF1B TMSB4X UBE2D1 UBTF
Entrez ID		4808	79101
HPRD ID		01213	14679
Ensembl ID		ENSG00000177551	ENSG00000166012
Uniprot IDs		A1PLF1 Q02577	A0A024R3A9 Q9H5J8
PDB IDs
Enriched GO Terms of Interacting Partners?
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