NFATC4 and GPR22

Data Source:
BioGRID (two hybrid)

		NFATC4	GPR22
Description		nuclear factor of activated T cells 4	G protein-coupled receptor 22
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Transcription Regulator Complex Cytosol Nuclear Speck	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Transcription Factor Binding Peroxisome Proliferator Activated Receptor Binding Sequence-specific Double-stranded DNA Binding	G Protein-coupled Receptor Activity Peptide Binding
	Biological Process	Branching Involved In Blood Vessel Morphogenesis Cytokine Production Regulation Of Transcription By RNA Polymerase II Inflammatory Response Heart Development Long-term Memory Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of Wnt Signaling Pathway Brain-derived Neurotrophic Factor Receptor Signaling Pathway Negative Regulation Of Protein Binding Positive Regulation Of Tumor Necrosis Factor Production Calcineurin-NFAT Signaling Cascade Cellular Response To UV Negative Regulation Of Chromatin Binding Negative Regulation Of Neuron Apoptotic Process Cellular Respiration Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Dendrite Morphogenesis Smooth Muscle Cell Differentiation Muscle Cell Development Long-term Synaptic Potentiation Cellular Response To Lithium Ion Negative Regulation Of Pri-miRNA Transcription By RNA Polymerase II Cellular Response To Ionomycin Negative Regulation Of Synapse Maturation Positive Regulation Of Apoptotic Signaling Pathway	G Protein-coupled Receptor Signaling Pathway Cell Projection Organization
Pathways
Drugs
Diseases
GWAS		Diastolic blood pressure ( 27841878) Height ( 20881960 25282103 23563607)	Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		12 interacting genes: CCNG1 CREBBP GATA4 GPR22 JUP MAPK14 MAPK8 MAPK9 NLGN3 NR1I2 YWHAQ YWHAZ	3 interacting genes: CEBPE NFATC4 TFAP2C
Entrez ID		4776	2845
HPRD ID		09096	03552
Ensembl ID		ENSG00000100968	ENSG00000172209
Uniprot IDs		Q14934	B3KV13 Q3KNS9 Q99680
PDB IDs		2YRP
Enriched GO Terms of Interacting Partners?
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