NFATC3 and TTF1

Data Source:
HPRD (in vivo)

		NFATC3	TTF1
Description		nuclear factor of activated T cells 3	transcription termination factor 1
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Cytoplasm Cytosol	Nucleus Nucleoplasm Nucleolus Cytosol Plasma Membrane
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding	DNA Binding Chromatin Binding Protein Binding
	Biological Process	Cytokine Production Regulation Of Transcription By RNA Polymerase II Inflammatory Response Multicellular Organism Development Calcineurin-NFAT Signaling Cascade Fc-epsilon Receptor Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Pri-miRNA Transcription By RNA Polymerase II Negative Regulation Of Vascular Associated Smooth Muscle Cell Differentiation	DNA-templated Transcription, Termination Termination Of RNA Polymerase I Transcription Negative Regulation Of DNA Replication Cellular Protein Metabolic Process
Pathways		Calcineurin activates NFAT Calcineurin activates NFAT FCERI mediated Ca+2 mobilization CLEC7A (Dectin-1) induces NFAT activation	ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression NoRC negatively regulates rRNA expression Surfactant metabolism RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Termination RNA Polymerase I Transcription Termination
Drugs
Diseases			Benign hereditary chorea
GWAS		Chronotype ( 30696823) Estimated glomerular filtration rate ( 31015462) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656) Urate levels ( 31578528)
Interacting Genes		6 interacting genes: CDK6 CSNK1A1 FOS MAPK8 MAPK9 TTF1	6 interacting genes: BAZ2A CAVIN1 KAT2B NFATC3 SMAD1 SMAD7
Entrez ID		4775	7270
HPRD ID		04077	02866
Ensembl ID		ENSG00000072736	ENSG00000125482
Uniprot IDs		B5B2S0 B5B2S1 Q12968	A0A024R8C1 A0A087WY09 Q15361
PDB IDs		2XRW 2XS0
Enriched GO Terms of Interacting Partners?
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