NEDD9 and DIMT1

Data Source:
HPRD (two hybrid)

		NEDD9	DIMT1
Description		neural precursor cell expressed, developmentally down-regulated 9	DIMT1 rRNA methyltransferase and ribosome maturation factor
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GO Annotations	Cellular Component	Spindle Pole Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Spindle Cytosol Plasma Membrane Focal Adhesion Cell Cortex Lamellipodium	Nucleoplasm Nucleolus Mitochondrial Matrix Cytosol
	Molecular Function	Protein Binding Protein Tyrosine Kinase Binding	RRNA (adenine-N6,N6-)-dimethyltransferase Activity RNA Binding 18S RRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase Activity
	Biological Process	Cytoskeleton Organization Cell Cycle Cell Adhesion Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Integrin-mediated Signaling Pathway Cell Migration Positive Regulation Of Cell Migration Regulation Of Growth Actin Filament Bundle Assembly Cell Division Positive Regulation Of Protein Tyrosine Kinase Activity Actin Filament Reorganization Activation Of GTPase Activity Positive Regulation Of Substrate Adhesion-dependent Cell Spreading	RRNA Methylation Positive Regulation Of RRNA Processing
Pathways			rRNA modification in the nucleus and cytosol
Drugs
Diseases
GWAS		Childhood dental caries in permanent teeth ( 29931343) Coronary artery disease ( 29212778) Diastolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) HIV-1 susceptibility ( 22174851) Macular thickness ( 30535121) Prostate cancer ( 25217961) Small cell lung carcinoma ( 28604730)
Interacting Genes		69 interacting genes: ABL1 ANKS1A APP AURKA BANP BCAR1 BCAR3 C19orf54 CDC42EP2 CDH1 CHAT CRK CRKL DIMT1 DMRTB1 DOCK9 DPPA4 ELSPBP1 EXOSC8 FAM102A FAM168B FOSB FYN FZR1 HOXA1 ID2 INCA1 ITCH KLHL20 KRT32 LCK LHX8 LYN MED19 MICAL1 NAB2 NBPF19 NCK1 NFKBIA NOTCH2NLA NOTCH3 PIK3CA PIK3R3 PRAM1 PRR20A PTK2 PTK2B PTPN11 PTPN12 PXN RAPGEF1 RBPMS REL RFX6 SH2D3C SMAD1 SMAD2 SMAD3 SNAPIN TBX19 TCF3 TFCP2 TRAF2 TRIM23 TRIM27 TRIP6 WWOX ZNF76 ZYX	2 interacting genes: APP NEDD9
Entrez ID		4739	27292
HPRD ID		11888	13676
Ensembl ID		ENSG00000111859	ENSG00000086189
Uniprot IDs		A0A024QZV9 A0A087WUD2 Q14511	A0A0C4DGB1 A8K9K8 Q9UNQ2
PDB IDs		2L81 5X3S	1ZQ9 6W6C 6W6F
Enriched GO Terms of Interacting Partners?
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