MYOD1 and CSRP3

Data Source:
HPRD (in vivo, in vitro)

		MYOD1	CSRP3
Description		myogenic differentiation 1	cysteine and glycine rich protein 3
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Euchromatin Nucleus Nucleoplasm Transcription Regulator Complex Myofibril	Nucleus Cytoplasm Cytoskeleton Z Disc
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Activating Transcription Factor Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding Protein Binding Chromatin DNA Binding Ubiquitin Protein Ligase Binding Nuclear Hormone Receptor Binding Protein Homodimerization Activity E-box Binding Sequence-specific Double-stranded DNA Binding Promoter-specific Chromatin Binding	Actin Binding Protein Binding Structural Constituent Of Muscle Telethonin Binding Identical Protein Binding Actinin Binding Metal Ion Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Transcription By RNA Polymerase II Protein Phosphorylation Muscle Organ Development Myoblast Fate Determination Skeletal Muscle Tissue Development Myoblast Fusion Cellular Response To Starvation Myotube Cell Development Myotube Differentiation Involved In Skeletal Muscle Regeneration Negative Regulation Of Chromatin Binding Skeletal Muscle Cell Differentiation Muscle Cell Fate Commitment Positive Regulation Of Skeletal Muscle Tissue Regeneration Regulation Of RNA Splicing Skeletal Muscle Fiber Adaptation Histone H3 Acetylation Histone H4 Acetylation Positive Regulation Of Myoblast Differentiation Positive Regulation Of Transcription By RNA Polymerase II Skeletal Muscle Fiber Development Positive Regulation Of Skeletal Muscle Fiber Development Positive Regulation Of Binding Positive Regulation Of Muscle Cell Differentiation Cellular Response To Tumor Necrosis Factor Cellular Response To Glucocorticoid Stimulus Cellular Response To Estradiol Stimulus Cellular Response To Oxygen Levels Positive Regulation Of Myoblast Fusion Positive Regulation Of SnRNA Transcription By RNA Polymerase II Negative Regulation Of Myoblast Proliferation	Regulation Of The Force Of Heart Contraction Cardiac Muscle Hypertrophy Cellular Calcium Ion Homeostasis Inflammatory Response Skeletal Muscle Tissue Development Insulin Receptor Signaling Pathway Actin Cytoskeleton Organization T-tubule Organization Protein Localization To Organelle Detection Of Muscle Stretch Glucose Homeostasis Sarcomere Organization Positive Regulation Of Transcription By RNA Polymerase II Cardiac Muscle Tissue Development Cardiac Myofibril Assembly Cardiac Muscle Contraction Muscle Tissue Development Protein Kinase C Signaling Regulation Of Protein Localization To Plasma Membrane
Pathways		Myogenesis Myogenesis
Drugs
Diseases			Hypertrophic cardiomyopathy (HCM)
GWAS		Body mass index ( 26426971) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917)	Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 32888494 27863252) Mean spheric corpuscular volume ( 32888494) Mosquito bite size ( 28199695) Red blood cell count ( 32888494 27863252)
Interacting Genes		67 interacting genes: AP1M1 ASCL3 BHLHA15 BHLHE40 BHLHE41 C2orf88 CALM1 CALM2 CALM3 CARM1 CDC34 CDK2 CDK4 CDKN1C CIB2 CREBBP CSRP3 ELSPBP1 EP300 EXOC3L1 FBXO32 FIGLA HAND1 HDAC1 HEY1 HSP90AA1 ID1 ID2 ID3 ID4 IFRD1 IGFN1 JUN KAT2B KAT5 KPNA3 LMO4 MDFI MEF2A MEF2C MOS MYOCD NCOR1 NCOR2 NR2F2 PHB2 POLR2G PRKCA PRMT5 PSMD4 PSME2 RB1 RORA RUNX1 RXRA SETD3 SMAD3 SMAD4 SMAD7 SP1 SRF STAT3 SUV39H1 TCF21 TCF3 TCF4 TWIST1	11 interacting genes: ACTN1 FHL1 HDAC4 LDHD LIMS1 MYF6 MYOD1 MYOG NHLH1 RIN3 SPTB
Entrez ID		4654	8048
HPRD ID		01166	07525
Ensembl ID		ENSG00000129152	ENSG00000129170
Uniprot IDs		P15172	A2TDB8 P50461
PDB IDs			2O10 2O13
Enriched GO Terms of Interacting Partners?
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