MYO7A and MYRIP

Data Source:
HPRD (in vitro)

		MYO7A	MYRIP
Description		myosin VIIA	myosin VIIA and Rab interacting protein
Image			No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Photoreceptor Inner Segment Cytoplasm Lysosomal Membrane Cytosol Microvillus Cell Cortex Actin Cytoskeleton Apical Plasma Membrane Myosin VII Complex Vesicle Photoreceptor Connecting Cilium Stereocilium Melanosome Synapse Stereocilium Base Upper Tip-link Density	Exocyst Photoreceptor Outer Segment Transport Vesicle Cortical Actin Cytoskeleton Dense Core Granule Melanosome Synapse Perinuclear Region Of Cytoplasm
	Molecular Function	Microfilament Motor Activity Protein Binding Calmodulin Binding ATP Binding Protein Domain Specific Binding Spectrin Binding Actin-dependent ATPase Activity Identical Protein Binding ADP Binding Protein N-terminus Binding Actin Filament Binding	Actin Binding Protein Binding Zinc Ion Binding Myosin Binding Protein Kinase A Binding
	Biological Process	Phagolysosome Assembly Intracellular Protein Transport Actin Filament Organization Lysosome Organization Sensory Organ Development Visual Perception Sensory Perception Of Sound Actin Filament-based Movement Vesicle Transport Along Actin Filament Cellular Protein Localization Eye Photoreceptor Cell Development Mechanoreceptor Differentiation Post-embryonic Animal Organ Morphogenesis Sensory Perception Of Light Stimulus Equilibrioception Pigment Granule Transport Auditory Receptor Cell Stereocilium Organization	Intracellular Protein Transport Positive Regulation Of Insulin Secretion
Pathways		The canonical retinoid cycle in rods (twilight vision)	Insulin processing
Drugs
Diseases		Usher syndrome (US) Deafness, autosomal dominant Deafness, autosomal recessive
GWAS		Lewy body disease ( 25188341) Post bronchodilator FEV1/FVC ratio ( 26634245) Tourette syndrome ( 30818990)	Acute lymphoblastic leukemia (childhood) ( 23007406) Information processing speed ( 21130836) Rapid automised naming of letters ( 30741946) Sleep-related phenotypes ( 17903308) Whole brain grey matter density ( 31530798)
Interacting Genes		12 interacting genes: ACTA1 CALM1 CDH23 KEAP1 KHDRBS1 LINC00839 MAP2 MYRIP PRKAR1A USH1C VEZT WHRN	5 interacting genes: C1orf216 MYO7A OIP5 RAB27A RAB27B
Entrez ID		4647	25924
HPRD ID		02043	14796
Ensembl ID		ENSG00000137474	ENSG00000170011
Uniprot IDs		Q13402	Q8NFW9
PDB IDs		5MV9
Enriched GO Terms of Interacting Partners?
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