H3-5 and KAT6A

Data Source:
BioGRID (enzymatic study)

		H3-5	KAT6A
Description		H3.5 histone	lysine acetyltransferase 6A
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GO Annotations	Cellular Component	Nucleosome Euchromatin Nucleus	Nucleosome Nucleus Nucleoplasm Nucleolus Cytosol PML Body Nuclear Speck MOZ/MORF Histone Acetyltransferase Complex
	Molecular Function	Protein Binding Nucleosomal DNA Binding Protein Heterodimerization Activity	DNA Binding Transcription Coregulator Activity Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Binding Transcription Factor Binding Zinc Ion Binding Acetyltransferase Activity Histone Binding
	Biological Process	Positive Regulation Of Cell Growth	DNA Packaging Nucleosome Assembly Protein Acetylation Histone Acetylation Myeloid Cell Differentiation Histone H3 Acetylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Cellular Senescence Regulation Of Signal Transduction By P53 Class Mediator
Pathways			HATs acetylate histones Regulation of TP53 Activity through Acetylation
Drugs
Diseases
GWAS			Sleep duration ( 30531941)
Interacting Genes		15 interacting genes: DAXX DNAJC9 FBLIM1 KAT6A KDM1A KDM4B NASP NSD3 PRMT5 PRMT6 PRMT7 SETMAR SMYD1 SMYD3 SUV39H1	19 interacting genes: AKT1 ATN1 ATXN1 CREBBP H3-4 H3-5 H3C1 H3C14 H4-16 H4C1 H4C9 HEMGN MAFK PML RERE RUNX1 SPI1 TP53 UBE2U
Entrez ID		440093	7994
HPRD ID		18443	03244
Ensembl ID		ENSG00000188375	ENSG00000083168
Uniprot IDs		Q6NXT2	A5PKX7 A5PLL3 Q92794
PDB IDs		2PUY 3KV4 4Z5T 5BWN 5BWO 5F6K 5I3L 6OI3	1M36 2LN0 2OZU 2RC4 3V43 4LJN 4LK9 4LKA 4LLB 5B75 5B76 5B77 5B78
Enriched GO Terms of Interacting Partners?
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