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MDFI and SPON1
Data Source:
BioGRID
(two hybrid)
MDFI
SPON1
Description
MyoD family inhibitor
spondin 1
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Extracellular Space
Endoplasmic Reticulum Lumen
Extracellular Matrix
Collagen-containing Extracellular Matrix
Molecular Function
Protein Binding
Transcription Factor Binding
Identical Protein Binding
Transcription Regulator Inhibitor Activity
Extracellular Matrix Structural Constituent
Protein Binding
Metal Ion Binding
LBD Domain Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Dorsal/ventral Axis Specification
Negative Regulation Of Wnt Signaling Pathway
Cytoplasmic Sequestering Of Transcription Factor
Negative Regulation Of DNA Binding
Embryonic Skeletal System Morphogenesis
Trophoblast Giant Cell Differentiation
Cell Adhesion
Positive Regulation Of Protein Processing
Positive Regulation Of Protein Binding
Negative Regulation Of Amyloid-beta Formation
Positive Regulation Of Amyloid Precursor Protein Catabolic Process
Pathways
Defective B3GALTL causes Peters-plus syndrome (PpS)
O-glycosylation of TSR domain-containing proteins
Drugs
Diseases
GWAS
Grapefruit juice consumption (
31046077
)
Subjective response to placebo treatment in childhood asthma (change in cough/wheeze) (
31557306
)
Alzheimer's disease (cognitive decline) (
23535033
)
Blood protein levels (
30072576
29875488
28240269
)
Blood protein levels in cardiovascular risk (
28369058
)
Bone mineral density (total hip) (
29883787
)
Brain connectivity (
23471985
)
Common carotid intima-media thickness in HIV negative individuals (
29206233
)
Glucagon levels in response to oral glucose tolerance test (fasting) (
29093273
)
Inflammatory biomarkers (
22228203
)
Metabolite levels (
23823483
)
Mosaic loss of chromosome Y (Y chromosome dosage) (
31624269
)
P wave terminal force (
28794112
)
Refractive error (
32231278
)
Response to TNF inhibitor in rheumatoid arthritis (change in swollen 28-joint count) (
30166627
)
Response to TNF inhibitor in rheumatoid arthritis (change in tender 28-joint count) (
30166627
)
Sense of smell (
26632684
)
Tuberculosis (
24057671
)
Interacting Genes
405 interacting genes:
AANAT
AASDHPPT
ABCF3
ABHD11
ABHD17A
ADAMTSL3
ADRA2C
AEBP2
AGXT
AKAP17A
AP5Z1
APLN
AQP1
AQP5
ARHGAP32
ARID5A
ARMC7
ATG12
ATN1
ATP5F1D
ATP6V0C
ATXN7L2
AVPI1
AXIN1
B3GNT9
BAALC
BAG3
BAHD1
BANP
BBS2
BCAM
BCL6
BCL6B
BEX1
BEX2
BEX3
C10orf62
C1orf216
C22orf39
C4orf45
C8orf33
C8orf48
CATSPER1
CBFA2T2
CBLL2
CBX2
CBX8
CC2D1B
CCDC116
CCDC120
CCDC185
CCDC187
CCDC198
CCDC33
CCER1
CCNL2
CDC20B
CDC37
CDC42EP1
CDCA7L
CDKL3
CEP57L1
CFAP206
CHIC2
CHP2
CHRNG
CLPB
CNNM3
CRACR2A
CREB5
CRH
CRX
CRY1
CSNK1G2-AS1
CSNK1G3
CTRC
CXCL16
CYBA
DAAM2
DBF4B
DCAF6
DCAF8
DCANP1
DDX19A
DHRS1
DKK1
DMRT3
DNAJB13
DNMT3A
DNPEP
DOCK2
DOK3
DUSP6
DYNLT4
EBI3
EFEMP2
EIF4A2
EIF4E2
ELOA
ENKD1
ETNK2
EWSR1
FAAP100
FADS6
FAM120AOS
FAM124B
FAM161A
FAM161B
FAM214B
FAM27E3
FAM90A1
FARS2
FASTK
FBXL18
FBXO34
FBXW5
FES
FEZF1
FNDC11
FOXD4
FOXD4L1
FOXD4L3
FOXD4L6
FZD9
GABRD
GATA1
GATA2
GDF15
GLIDR
GLRX3
GNAI2
GNE
GNG5
GPANK1
GPATCH2L
GPRIN2
GREM1
GTF3C5
HAPLN2
HASPIN
HEYL
HHEX
HHLA3
HNRNPLL
HOXA1
HOXB9
HPCAL1
HTR1B
HYPK
IFRD2
ILF3
INTS11
IQUB
ITGB4
JOSD1
KANSL1
KAT5
KCTD7
KIAA0040
KIAA0408
KIF1A
KLHL38
KPNA2
KRAS
KRT77
LAMB3
LASP1
LCE1A
LCE1B
LCE1D
LCE1F
LCE2B
LCE3A
LCE3C
LCE3D
LCE3E
LCE4A
LIMS2
LIN7A
LINC00636
LINC01588
LMO3
LRCH4
LRRN4
MACIR
MAGEC3
MAGED1
MAGEF1
MAPK1
MAPKBP1
MBD3L2
MCM5
MEOX2
METTL17
MFSD3
MGAT5B
MRPL20-AS1
MVP
MXI1
MYF5
MYOD1
MYOG
MYPOP
NAB2
NDUFA7
NECTIN2
NEU4
NIBAN3
NKD1
NOL4L-DT
NPDC1
NPEPL1
NR1H2
NR1H3
NSD1
NTAQ1
NUBP2
NUFIP2
ODAD4
ODAPH
ODF1
ODF3B
OLIG3
OTX1
PARP11
PATZ1
PBXIP1
PCSK5
PDGFA
PDGFB
PDIA5
PDS5A
PELI2
PGLS
PHF1
PHLDA1
PIBF1
PID1
PIDD1
PIH1D2
PIN1
PKD2
PLEKHG4
POLL
POM121L8P
PRKAB2
PRPF18
PRPF31
PRR34
PTK7
PTPMT1
RABL6
RAC1
RASD1
REG3A
REX1BD
RFX2
RHOXF2
RIN1
RIPPLY1
RNF111
RNF6
RTP5
SAPCD2
SCAMP4
SCNM1
SELENOM
SEMA3B
SERF2
SFI1
SHFL
SHMT1
SIX1
SLC13A5
SLC15A3
SLC25A10
SLC35A2
SLC9A1
SMYD1
SNX18
SOCS7
SPATA24
SPATA3
SPATA8
SPG7
SPON1
SPRED2
SPRY1
SPRY2
SUOX
TACO1
TAP1
TASOR2
TBC1D3B
TBC1D3G
TCEANC
TCF3
TEAD4
TEDC2
TGIF1
TH
THAP7
THEG
TIE1
TINAGL1
TLE5
TMEM241
TMIE
TNNI1
TNP2
TOR1A
TRAF3IP2
TRIB3
TRPC1
TRPV6
TSC2
TSFM
TSGA10IP
TSPAN4
TSPYL1
TSPYL6
TTC23
TTLL10
TUSC2
TXN2
TYMSOS
TYRO3
USP20
USP6
VASN
VGLL3
VHL
VPS72
VSTM4
WDFY3
WNT11
YPEL3
YY1
ZBBX
ZBTB24
ZBTB25
ZBTB42
ZBTB9
ZC3HAV1
ZDHHC1
ZFYVE26
ZIM2
ZNF101
ZNF12
ZNF124
ZNF136
ZNF138
ZNF155
ZNF205
ZNF221
ZNF223
ZNF23
ZNF230
ZNF264
ZNF266
ZNF330
ZNF408
ZNF414
ZNF417
ZNF426
ZNF433
ZNF438
ZNF439
ZNF440
ZNF441
ZNF446
ZNF461
ZNF479
ZNF490
ZNF491
ZNF497
ZNF512B
ZNF524
ZNF559
ZNF564
ZNF572
ZNF575
ZNF578
ZNF580
ZNF581
ZNF587
ZNF607
ZNF613
ZNF646
ZNF648
ZNF662
ZNF669
ZNF670
ZNF679
ZNF688
ZNF696
ZNF707
ZNF764
ZNF784
ZNF785
ZNF786
ZNF79
ZNF837
ZNF844
ZNHIT1
4 interacting genes:
APP
CYSRT1
MDFI
MEOX2
Entrez ID
4188
10418
HPRD ID
07280
16087
Ensembl ID
ENSG00000112559
ENSG00000262655
Uniprot IDs
A0A024RCY2
B1AKB6
Q99750
Q9HCB6
PDB IDs
2ZOT
2ZOU
3COO
3Q13
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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