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MCM7 and MCMBP
Data Source:
BioGRID
(affinity chromatography technology, pull down, two hybrid)
MCM7
MCMBP
Description
minichromosome maintenance complex component 7
minichromosome maintenance complex binding protein
Image
GO Annotations
Cellular Component
Chromosome, Telomeric Region
Chromatin
Nucleus
Nucleoplasm
Nucleolus
Cytosol
Membrane
MCM Complex
CMG Complex
Nucleus
Nucleoplasm
Cytosol
Cell Junction
MCM Complex
Molecular Function
DNA Binding
DNA Helicase Activity
DNA Replication Origin Binding
Single-stranded DNA Binding
Protein Binding
ATP Binding
Single-stranded 3'-5' DNA Helicase Activity
Chromatin Binding
Protein Binding
Biological Process
G1/S Transition Of Mitotic Cell Cycle
Double-strand Break Repair Via Break-induced Replication
DNA Replication
Pre-replicative Complex Assembly Involved In Nuclear Cell Cycle DNA Replication
DNA Unwinding Involved In DNA Replication
DNA Replication Initiation
DNA Strand Elongation Involved In DNA Replication
Cellular Response To DNA Damage Stimulus
Cell Population Proliferation
Regulation Of Phosphorylation
Response To Drug
Cellular Response To Epidermal Growth Factor Stimulus
Cellular Response To Xenobiotic Stimulus
DNA-dependent DNA Replication
Sister Chromatid Cohesion
Cell Division
Pathways
Activation of ATR in response to replication stress
Unwinding of DNA
Assembly of the pre-replicative complex
Orc1 removal from chromatin
Activation of the pre-replicative complex
Switching of origins to a post-replicative state
Drugs
Diseases
GWAS
Brain morphology (MOSTest) (
32665545
)
Refractive error (
32231278
)
Subcortical volume (MOSTest) (
32665545
)
Body size at age 10 (
32376654
)
Height (
28552196
)
Interacting Genes
77 interacting genes:
ABI2
AK8
APP
ASB8
C8orf34
CCDC102B
CCND1
CCNH
CDC42
CDC45
CDC6
CDC7
CDK7
CDKN1B
CEP68
CHEK1
COG6
CRLS1
DBF4
DNAAF6
DUX4
ELOC
ESCO2
FHL2
GOLGA2
H3-4
HIF1A
IKBKG
IKZF3
INTS6
KIFC3
LINC01554
LNX2
MAGEA6
MBIP
MCM10
MCM2
MCM3
MCM4
MCM5
MCM6
MCM8
MCMBP
MEOX2
MIPOL1
MNAT1
NAB2
NFKBIA
ORC1
ORC2
ORC3
ORC4
ORC5
ORC6
PLK1
PNMA1
RAD17
RB1
RBL1
RBL2
RBM8A
RBPMS
RINT1
RPA1
SMC1A
SNTA1
SP2
SSX2IP
TFIP11
TREX1
TRIM27
TRIM54
TRIM55
TRIM63
UBE3A
UBQLN1
USHBP1
15 interacting genes:
ASL
DBF4
DDIT3
FKBP5
KEAP1
MCM3
MCM4
MCM5
MCM6
MCM7
PRTFDC1
RWDD2A
SNW1
USP7
ZNF474
Entrez ID
4176
79892
HPRD ID
01154
07624
Ensembl ID
ENSG00000166508
ENSG00000197771
Uniprot IDs
A0A0S2Z4A5
C6EMX8
P33993
A0A0S2Z5P5
Q9BTE3
PDB IDs
6XTX
6XTY
4KG9
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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