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MATK and HSPA9
Data Source:
BioGRID
(pull down)
MATK
HSPA9
Description
megakaryocyte-associated tyrosine kinase
heat shock protein family A (Hsp70) member 9
Image
GO Annotations
Cellular Component
Cytosol
Membrane
SAM Complex
Nucleolus
Cytoplasm
Mitochondrion
Mitochondrial Matrix
Focal Adhesion
Mitochondrial Nucleoid
Extracellular Exosome
MIB Complex
Molecular Function
Protein Tyrosine Kinase Activity
Non-membrane Spanning Protein Tyrosine Kinase Activity
Protein Binding
ATP Binding
RNA Binding
Protein Binding
ATP Binding
ATPase Activity
Heat Shock Protein Binding
Ubiquitin Protein Ligase Binding
Protein Folding Chaperone
Unfolded Protein Binding
Misfolded Protein Binding
Biological Process
Protein Phosphorylation
Positive Regulation Of Cell Population Proliferation
Peptidyl-tyrosine Phosphorylation
ERBB2 Signaling Pathway
Protein Export From Nucleus
Inner Mitochondrial Membrane Organization
Iron-sulfur Cluster Assembly
Erythrocyte Differentiation
Cellular Response To Unfolded Protein
Interleukin-12-mediated Signaling Pathway
Protein Refolding
Negative Regulation Of Apoptotic Process
Regulation Of Erythrocyte Differentiation
Negative Regulation Of Erythrocyte Differentiation
Chaperone Cofactor-dependent Protein Refolding
Negative Regulation Of Hematopoietic Stem Cell Differentiation
Negative Regulation Of Hemopoiesis
Pathways
Downregulation of ERBB2 signaling
Mitochondrial protein import
Regulation of HSF1-mediated heat shock response
Cristae formation
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs
Fostamatinib
Diseases
GWAS
Obesity-related traits (
23251661
)
Autism spectrum disorder or schizophrenia (
28540026
)
Cerebrospinal AB1-42 levels in Alzheimer's disease dementia (
29274321
)
Schizophrenia (
25056061
29483656
)
Interacting Genes
24 interacting genes:
AKT1
AR
CACNA1A
CD36
ERBB2
ERBB3
ERBB4
EWSR1
FRS3
HSPA5
HSPA9
ILK
KIT
LRRK1
LRRK2
LYN
MET
NTRK1
PTK2B
PTPRD
PXN
SIRPA
SMURF1
SRC
26 interacting genes:
APP
DNAJC19
DNLZ
ERBB2
ERCC6
FGF1
HSP90B1
HSPBP1
LAMTOR5
LINC01554
LSM8
MATK
MVD
NELFB
PTPN11
PTPRF
SIRPA
STUB1
SUMO2
SUMO4
SUPT6H
TIMM44
TP53
XPO1
YKT6
YWHAG
Entrez ID
4145
3313
HPRD ID
02496
02770
Ensembl ID
ENSG00000007264
ENSG00000113013
Uniprot IDs
F1T0G6
P42679
A0A384P5G6
P38646
PDB IDs
1JWO
1X6G
3US4
3N8E
4KBO
6NHK
6P2U
6PMT
Enriched GO Terms of Interacting Partners
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