MAK and NDUFB7

Data Source:
BioGRID (two hybrid)

		MAK	NDUFB7
Description		male germ cell associated kinase	NADH:ubiquinone oxidoreductase subunit B7
Image		No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Photoreceptor Inner Segment Nucleus Cytoplasm Centrosome Cilium Axoneme Midbody Motile Cilium Photoreceptor Connecting Cilium Mitotic Spindle	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex I Mitochondrial Intermembrane Space
	Molecular Function	Transcription Coactivator Activity Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Metal Ion Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	Protein Binding NADH Dehydrogenase (ubiquinone) Activity
	Biological Process	MAPK Cascade Protein Phosphorylation Multicellular Organism Development Spermatogenesis Cell Differentiation Intracellular Signal Transduction Intraciliary Transport Photoreceptor Cell Maintenance Positive Regulation Of Transcription, DNA-templated Protein Autophosphorylation Cilium Assembly Negative Regulation Of Non-motile Cilium Assembly	Mitochondrial Electron Transport, NADH To Ubiquinone Mitochondrial Respiratory Chain Complex I Assembly
Pathways			Respiratory electron transport Complex I biogenesis
Drugs			NADH
Diseases
GWAS		Menopause (age at onset) ( 26414677) Recurrent major depressive disorder ( 29317602) Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261)
Interacting Genes		9 interacting genes: ANAPC11 APP FBXO7 FZR1 NDUFB7 PPP2CB SERINC1 SLAMF7 SND1	41 interacting genes: AGBL2 ANKRD36B ATG9A C1orf109 CAPN1 CCDC24 CCNC CDCA7L CDKN2D CHIC2 CINP CKAP4 CTNNA3 ENKD1 FAM161B FAM90A1 GEM GPATCH2L GYS1 KRTAP10-10 LMO2 MAGOHB MAK MEIS2 MKRN3 MLKL NDUFB2 NFKBIB NFKBID RCOR3 RECK RIPPLY1 RIPPLY2 SCNM1 SPRED2 STRA6 TLE5 ZNF330 ZNF417 ZNF564 ZNF587
Entrez ID		4117	4713
HPRD ID		01101	11957
Ensembl ID		ENSG00000111837	ENSG00000099795
Uniprot IDs		A0A140VK28 F8VBW7 P20794	P17568
PDB IDs			5XTC 5XTD 5XTH 5XTI
Enriched GO Terms of Interacting Partners?
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