MIR106B and SF3A3

Data Source:
BioGRID (unspecified method)

		MIR106B	SF3A3
Description		microRNA 106b	splicing factor 3a subunit 3
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Extracellular Vesicle	Nucleus Nucleoplasm Spliceosomal Complex U2 SnRNP Nuclear Speck U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	MRNA 3'-UTR Binding MRNA Binding Involved In Posttranscriptional Gene Silencing	RNA Binding Protein Binding Zinc Ion Binding
	Biological Process	Negative Regulation Of Gene Expression Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Negative Regulation Of Angiogenesis Negative Regulation Of Interleukin-8 Production Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Negative Regulation Of Peptidyl-tyrosine Phosphorylation Cellular Response To Hypoxia Cellular Response To Amyloid-beta Regulation Of Endothelial Cell Apoptotic Process	RNA Splicing, Via Transesterification Reactions MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome MRNA Processing U2-type Prespliceosome Assembly
Pathways			mRNA Splicing - Major Pathway
Drugs			Phenethyl Isothiocyanate
Diseases
GWAS			Coronary artery disease ( 29212778 33020668) Heel bone mineral density ( 30598549 28869591) Height ( 28552196) Pulse pressure ( 28135244) Systolic blood pressure ( 30578418)
Interacting Genes		97 interacting genes: AIMP1 AQR C1QBP CCAR1 CDC40 CDC5L CELF1 CHERP CPSF1 DARS1 DDX1 DDX21 DDX23 DDX3X DDX3Y DHX36 DHX37 EDC4 EIF2AK2 EPRS1 ERAL1 ESRP1 FUS G3BP2 GRSF1 HARS2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI2 NOL6 NONO NUDT21 NUFIP2 PDCD11 PGAM5 PLRG1 PRMT1 PTBP1 PTBP3 PUF60 PUM1 PURA QARS1 RARS1 RBM10 RBM14 RBM17 RBM4 RTCA RTCB SF1 SF3A1 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 SUGP2 SYNCRIP TAF15 TIAL1 TRA2A TRA2B U2SURP UPF1 UTP20 XAB2 YBX1 YBX2 YBX3 ZFR ZNF346	38 interacting genes: ADAP1 APBB1 APP CCDC85B HSPB1 MIR106B MIR107 MIR141 MIR145 MIR155 MIR199A1 MIR200A MIR200C MIR206 MIR214 MIR221 MIR34A MIR34B MIR429 MIR451A MIR7-1 MIRLET7A2 MIRLET7E MIRLET7G MIRLET7I MTNR1B PRMT5 PRPF40A SF3A1 SREK1 TADA2A TCERG1 TRIM69 U2AF1 VAV2 WBP4 ZDHHC17 ZNF212
Entrez ID		406900	10946
HPRD ID			10411
Ensembl ID		ENSG00000208036	ENSG00000183431
Uniprot IDs			B4DW90 Q12874
PDB IDs			2DT7 5Z56 5Z57 5Z58 6AH0 6AHD 6FF7 6QX9 6Y50 6Y53 6Y5Q
Enriched GO Terms of Interacting Partners?
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